Description

1H-Thieno[3,4-D]Imidazole-4-Pentanoic Acid, 1-[Bis(4-Methoxyphenyl)Phenylmethyl]Hexahydro-2-Oxo-, [3As-(3Aa,4B,6Aa)]- is a high-purity, advanced pharmaceutical intermediate with a complex heterocyclic structure. This compound is critical for the synthesis of specialized active pharmaceutical ingredients (APIs) requiring precise stereochemistry and functional group compatibility. It is primarily utilized by research institutions and pharmaceutical manufacturers engaged in the development of novel therapeutic agents, particularly in areas requiring sophisticated organic synthesis.

Application

• Key Intermediate in Pharmaceutical Synthesis: Serves as a crucial building block for the production of complex, high-value APIs, especially those targeting specific biological pathways.
• Research & Development (R&D): Used in medicinal chemistry for the discovery and optimization of new drug candidates, leveraging its unique imidazole-thiophene fused ring system.
• Process Chemistry & Scale-Up: Employed in the development and optimization of scalable synthetic routes for commercial drug manufacturing.
• Contract Manufacturing Organizations (CMOs): Supplied to CMOs producing custom APIs for clinical trials and commercial supply under GMP guidelines.
• Academic Research: Utilized in university and institutional labs for studying heterocyclic chemistry, reaction mechanisms, and developing new synthetic methodologies.

Basic Information

Product Name	1H-Thieno[3,4-D]Imidazole-4-Pentanoic Acid, 1-[Bis(4-Methoxyphenyl)Phenylmethyl]Hexahydro-2-Oxo-, [3As-(3Aa,4B,6Aa)]-
CAS No.	144095-63-6
Molecular Formula	C30H30N2O5S
Molecular Weight	530.64 g/mol
Synonyms	(3aS,4R,6aR)-1-[Bis(4-methoxyphenyl)(phenyl)methyl]hexahydro-2-oxo-1H-thieno[3,4-d]imidazole-4-pentanoic acid; Biotin-PEG4-TAMRA Precursor Intermediate; Biotinylation Reagent Intermediate; Trityl-protected Biotin Derivative; Thienoimidazole Pentanoic Acid Derivative; [3As-(3Aa,4B,6Aa)]- Stereoisomer
EINECS	Contact for details

Quality Control

Our products undergo rigorous quality testing to ensure compliance with industry standards for pharmaceutical intermediates. Each batch is characterized using advanced analytical techniques including HPLC, NMR, and mass spectrometry to confirm identity, purity, and stereochemical integrity. Certificates of Analysis (COA) are available upon request, detailing batch-specific results. We support development under quality systems suitable for cGMP manufacturing.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider desiccants or an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Assay (HPLC)	≥ 98.0%
Purity (HPLC, Area %)	≥ 99.0%
Single Maximum Impurity	≤ 0.5%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.