Description

2-Amino-4-Pentenoic Acid Hydrochloride is a high-purity, non-proteinogenic amino acid derivative in its stable hydrochloride salt form. This compound is a versatile chiral building block prized for its terminal alkene functionality, which enables diverse chemical transformations, including cross-coupling and click chemistry reactions. It is essential for researchers and manufacturers in pharmaceutical development, peptide synthesis, and the creation of novel bioactive molecules and chemical probes.

Application

• Pharmaceutical Intermediates: A key chiral synthon for the synthesis of novel active pharmaceutical ingredients (APIs) and drug candidates.
• Peptide Chemistry: Used in solid-phase and solution-phase peptide synthesis to incorporate unsaturated side chains for structural modification or conjugation.
• Bioconjugation & Probe Development: The terminal alkene group serves as a handle for site-specific bioconjugation via thiol-ene or other reactions to create labeled proteins or diagnostic probes.
• Chemical Biology Research: Employed as a building block for designing enzyme inhibitors, receptor ligands, and other tools to study biological pathways.
• Agrochemical Synthesis: Acts as an intermediate in the development of advanced crop protection agents and specialty agrochemicals.
• Material Science: A potential monomer or cross-linker in the synthesis of specialized polymers with unique properties.

Basic Information

Product Name	2-Amino-4-Pentenoic Acid Hydrochloride
CAS No.	144073-09-6
Molecular Formula	C5H9NO2 • HCl
Molecular Weight	151.59 g/mol (Free base: 115.13 g/mol)
Synonyms	4-Pentenoic acid, 2-amino-, hydrochloride; (S)-2-Amino-4-pentenoic acid hydrochloride; 2-Amino-4-pentenoic acid HCl; Allylglycine hydrochloride; (S)-Allylglycine hydrochloride; 2-Amino-4-pentenoic acid monohydrochloride; L-2-Amino-4-pentenoic acid hydrochloride
EINECS	Contact for details

Quality Control

Our 2-Amino-4-Pentenoic Acid Hydrochloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and chiral integrity, to ensure it meets exacting standards for research and production. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive); keep the container tightly sealed in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Chiral Purity (HPLC)	≥99.0% ee
Water Content (KF)	≤1.0%
Residue on Ignition	≤0.1%
Heavy Metals (as Pb)	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.