Description

n-Acetyl-2-o-Methyl-α-Neuraminic Acid is a chemically modified derivative of sialic acid, a critical carbohydrate moiety in glycobiology. This compound is essential for research and development in the life sciences, serving as a key intermediate and reference standard for studying glycosylation patterns, cell signaling, and pathogen-host interactions. It is primarily utilized by biopharmaceutical companies, academic research institutions, and diagnostic developers focused on glycoprotein therapeutics, vaccine development, and biomarker discovery.

Application

• Glycobiology Research: Used as a critical intermediate or substrate in enzymatic studies and metabolic pathway analysis of sialic acids.
• Pharmaceutical Development: Serves as a building block or reference standard in the synthesis of novel glycoconjugate vaccines and therapeutic antibodies.
• Diagnostic Reagent Manufacturing: Employed in the production of diagnostic kits and assays that detect sialic acid-related enzymes or biomarkers.
• Enzymology Studies: Acts as a specific substrate or inhibitor for sialidases (neuraminidases) and sialyltransferases.
• Biochemical Tool: Utilized in the study of cell surface recognition, microbial adhesion, and immune system modulation.
• Standards and Calibration: Provides a high-purity chemical standard for analytical methods like HPLC and MS in quality control laboratories.

Basic Information

Product Name	n-Acetyl-2-o-Methyl-α-Neuraminic Acid
CAS No.	143791-32-6
Molecular Formula	C13H23NO9
Molecular Weight	337.32 g/mol
Synonyms	2-O-Methyl-N-acetylneuraminic acid; 2-O-Methyl-N-acetyl-α-neuraminic acid; 2-O-Methyl-5-acetamido-3,5-dideoxy-D-glycero-α-D-galacto-non-2-ulopyranosonic acid; 2-OMe Neu5Ac; Methylated Sialic Acid Derivative; N-Acetyl-2-O-methylneuraminic acid; α-2-O-Methyl-N-acetylneuraminic acid
EINECS	Contact for details

Quality Control

Our n-Acetyl-2-o-Methyl-α-Neuraminic Acid is produced under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and MS for structural confirmation, and tests for residual solvents and moisture to ensure it meets the stringent requirements of research and development applications. Certificates of Analysis (COA) with detailed chromatographic data are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C. This product is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability and purity. For long-term storage, consider desiccation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
Specific Rotation	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.