Description

Fmoc-10-Adc-Oh CAS NO 143688-82-8 is a high-purity, protected amino acid derivative specifically designed for solid-phase peptide synthesis (SPPS). This compound is critical for the controlled introduction of the non-proteinogenic amino acid 10-Aminodecanoic acid (10-Adc) into peptide chains, enabling the synthesis of peptides with tailored properties. It is an essential building block for researchers and manufacturers in the pharmaceutical, biotechnology, and life sciences sectors developing therapeutic peptides, diagnostic tools, and advanced biomaterials.

Application

• Solid-Phase Peptide Synthesis (SPPS): Primary use as a protected building block for the incorporation of 10-Aminodecanoic acid into custom peptide sequences.
• Therapeutic Peptide Development: Enables the creation of novel peptide-based drugs, including hormone analogs, antimicrobial peptides, and targeted therapeutics.
• Bioconjugation and Linker Chemistry: Serves as a spacer or linker molecule for attaching functional groups, labels (e.g., fluorophores), or drugs to peptides, proteins, or other biomolecules.
• Material Science Research: Used in the synthesis of peptide-polymer conjugates and self-assembling biomaterials for drug delivery systems and tissue engineering scaffolds.
• Chemical Biology Probes: A key reagent for producing labeled peptides used in studying protein-protein interactions, enzyme activity, and cellular processes.
• Process Development & Scale-Up: Supports R&D and manufacturing scale-up for peptide APIs (Active Pharmaceutical Ingredients) under cGMP conditions.

Basic Information

Item	Detail
Product Name	Fmoc-10-Adc-Oh
CAS No.	143688-82-8
Molecular Formula	C25H31NO4
Molecular Weight	409.52 g/mol
Synonyms	Fmoc-10-Aminodecanoic acid; N-[(9H-Fluoren-9-ylmethoxy)carbonyl]-10-aminodecanoic acid; Fmoc-10-amino-n-decanoic acid; Fmoc-Adc(10)-OH; N-Fmoc-10-aminodecanoic acid; 10-[(9-Fluorenylmethyloxycarbonyl)amino]decanoic acid; (9H-Fluoren-9-yl)methyl N-(9-carboxynonyl)carbamate
EINECS	Contact for details

Quality Control

Every batch of Fmoc-10-Adc-Oh is manufactured and tested to meet stringent quality standards suitable for advanced research and pharmaceutical applications. Our rigorous quality testing includes multiple orthogonal analytical methods to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing purity (typically ≥98% by HPLC), chiral purity, and impurity profiles is provided with each shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store at 2-8°C in a dry, cool place. This product is hygroscopic (moisture-sensitive) and light-sensitive (store away from light). For long-term storage under inert atmosphere, consider sealing under argon or nitrogen.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Chiral Purity	≥ 99.0%
Water Content (KF)	≤ 1.0%
Heavy Metals	≤ 20 ppm
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.