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N,N'-(3-Fluoro-4-Methyl-8-Oxo-5,6,7,8-Tetrahydronaphthalene-1,7-Diyl)Diacetamide CAS NO 143655-70-3


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CAS No.:143655-70-3

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

N,N'-(3-Fluoro-4-Methyl-8-Oxo-5,6,7,8-Tetrahydronaphthalene-1,7-Diyl)Diacetamide is a high-purity, advanced pharmaceutical intermediate characterized by its complex tetrahydronaphthalene core structure. This compound is critical for the synthesis of novel active pharmaceutical ingredients (APIs), particularly in research and development targeting specific therapeutic pathways. It is primarily utilized by pharmaceutical R&D laboratories, fine chemical manufacturers, and academic research institutions engaged in medicinal chemistry and process development.

Application

  • Pharmaceutical Intermediate: Serves as a key building block in the synthesis of complex drug candidates, especially those with tetrahydronaphthalene or related scaffolds.
  • Medicinal Chemistry Research: Used in the discovery and optimization of new chemical entities (NCEs) for various therapeutic targets.
  • Process Chemistry Development: Employed in scaling up synthetic routes for potential APIs during clinical trial material manufacturing.
  • Reference Standard: Acts as a high-purity analytical standard for quality control and method validation in pharmaceutical analysis.
  • Organic Synthesis: Utilized in academic and industrial research for constructing complex polycyclic molecules and studying structure-activity relationships (SAR).

Basic Information

Product Name N,N'-(3-Fluoro-4-Methyl-8-Oxo-5,6,7,8-Tetrahydronaphthalene-1,7-Diyl)Diacetamide
CAS No. 143655-70-3
Molecular Formula C17H17FN2O3
Molecular Weight 316.33 g/mol
Synonyms 1,7-Bis(acetamido)-3-fluoro-4-methyl-5,6,7,8-tetrahydronaphthalen-8-one; 3-Fluoro-4-methyl-8-oxo-1,7-bis(acetylamino)-5,6,7,8-tetrahydronaphthalene; 3-Fluoro-4-methyl-1,7-diacetamido-5,6,7,8-tetrahydro-8-naphthalenone; 143655-70-3; N,N'-(3-Fluoro-4-methyl-8-oxo-1,4,5,8-tetrahydronaphthalene-1,7-diyl)diacetamide (alternative numbering); Fluorinated tetrahydronaphthalene diacetamide derivative.
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Quality Control

Our N,N'-(3-Fluoro-4-Methyl-8-Oxo-5,6,7,8-Tetrahydronaphthalene-1,7-Diyl)Diacetamide is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for pharmaceutical R&D. A comprehensive Certificate of Analysis (COA) detailing purity, impurities, and physical characteristics is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). The compound may be light-sensitive and should be handled accordingly to maintain stability.

Specification

Item Specification
Appearance White to off-white powder
Identification (IR) Conforms to structure
Purity (HPLC) ≥ 97.0%
Related Substances (HPLC) Total impurities ≤ 3.0%
Loss on Drying ≤ 0.5%
Residue on Ignition ≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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