Description

5-{[(tert-Butoxy)Carbonyl]Amino}-2-Methylbenzoic Acid CAS NO 143617-90-7 is a high-purity, protected amino acid derivative featuring a tert-butoxycarbonyl (Boc) protecting group on the amine and a carboxylic acid functionality. This compound is a critical building block in modern organic synthesis, particularly for the controlled assembly of complex molecules in pharmaceutical research and development. It is primarily utilized by medicinal chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials industries for peptide synthesis and as a key intermediate in active pharmaceutical ingredient (API) manufacturing.

Application

• Pharmaceutical Intermediate: Serves as a crucial building block in the synthesis of novel drug candidates, particularly in peptide and small molecule drug discovery.
• Peptide Synthesis: Used as a Boc-protected amino acid derivative for solid-phase and solution-phase peptide synthesis, enabling the controlled elongation of peptide chains.
• Chemical Research & Development: Acts as a versatile synthon in academic and industrial R&D for creating complex organic structures and exploring new chemical spaces.
• Agrochemical Synthesis: Employed as an intermediate in the development of advanced crop protection agents and herbicides.
• Protecting Group Chemistry: Utilized in multi-step synthetic routes where the Boc group provides temporary protection for amine functionalities, which can be selectively removed under mild acidic conditions.

Basic Information

Product Name	5-{[(tert-Butoxy)Carbonyl]Amino}-2-Methylbenzoic Acid
CAS No.	143617-90-7
Molecular Formula	C14H19NO4
Molecular Weight	265.31 g/mol
Synonyms	5-[(tert-Butoxycarbonyl)amino]-2-methylbenzoic acid; 5-(Boc-amino)-2-methylbenzoic acid; 2-Methyl-5-[(tert-butoxycarbonyl)amino]benzoic acid; Boc-5-Amino-2-methylbenzoic Acid; 5-Amino-2-methylbenzoic acid N-Boc derivative; tert-Butyl (3-methyl-4-carboxyphenyl)carbamate; CAS 143617-90-7
EINECS	Contact for details

Quality Control

Our 5-{[(tert-Butoxy)Carbonyl]Amino}-2-Methylbenzoic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and tests for residual solvents and heavy metals to ensure it meets the high standards required for research and production. Certificates of Analysis (COA) documenting full specifications are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); keep the container tightly sealed under an inert atmosphere if possible to maximize shelf life.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥98.0%
Water Content (KF)	≤0.5%
Residual Solvents (GC)	Meets ICH guidelines
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.