Description

(1R,2R)-(+)-N,N'-Di-p-Tosyl-1,2-Cyclohexanediamine is a high-purity, chiral diamine derivative featuring tosyl-protected amine groups. This compound is a critical chiral ligand and building block in asymmetric synthesis, enabling the production of enantiomerically pure pharmaceuticals and fine chemicals. It is primarily utilized by research institutions and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries for catalyst development and the synthesis of complex organic molecules.

Application

• Asymmetric Catalysis: Serves as a privileged chiral ligand or precursor for metal-catalyzed asymmetric reactions, including hydrogenation, epoxidation, and C-C bond formation.
• Pharmaceutical Intermediates: A key building block in the synthesis of enantiomerically pure active pharmaceutical ingredients (APIs) for various therapeutic areas.
• Chiral Auxiliary: Used to induce chirality in synthetic pathways for the preparation of complex natural products and fine chemicals.
• Agrochemical Synthesis: Employed in the research and development of chiral pesticides and herbicides to enhance efficacy and reduce environmental impact.
• Material Science Research: Investigated as a monomer or functional component for creating chiral polymers and advanced materials with specific optical properties.
• Academic & Process Chemistry: A valuable reagent for methodological development in academic laboratories and for scaling up chiral processes in industrial settings.

Basic Information

Product Name	(1R,2R)-(+)-N,N'-Di-p-Tosyl-1,2-Cyclohexanediamine
CAS No.	143585-47-1
Molecular Formula	C₂₀H₂₆N₂O₄S₂
Molecular Weight	422.56 g/mol
Synonyms	(1R,2R)-1,2-Diaminocyclohexane N,N'-bis(4-methylbenzenesulfonamide); (1R,2R)-(-)-1,2-Diaminocyclohexane N,N'-di-p-toluenesulfonamide; (R,R)-Ts-DACH; (1R,2R)-N,N'-Bis(4-tolylsulfonyl)-1,2-diaminocyclohexane; (1R,2R)-(-)-1,2-Diaminocyclohexane-N,N'-bis(p-toluenesulfonamide); (R,R)-DACH-Ts₂; (1R,2R)-1,2-Bis[(4-methylphenyl)sulfonylamino]cyclohexane; (R,R)-N,N'-Di-p-toluenesulfonyl-1,2-diaminocyclohexane
EINECS	Contact for details

Quality Control

Our (1R,2R)-(+)-N,N'-Di-p-Tosyl-1,2-Cyclohexanediamine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity verification by HPLC, to ensure compliance with exacting standards for research and process chemistry. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and chiral excess is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); keep the container tightly sealed in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.