Description

1-Benzoyl-6-Bromo-7-Azaindole is a high-purity, advanced pharmaceutical intermediate characterized by its distinct azaindole core functionalized with bromo and benzoyl groups. This compound is of significant value in medicinal chemistry for its role as a versatile building block in the synthesis of complex bioactive molecules. It is primarily sought after by research institutions and pharmaceutical companies engaged in the development of kinase inhibitors and other targeted therapeutic agents.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel kinase inhibitors for oncology and inflammatory disease research.
• Medicinal Chemistry Building Block: Used in structure-activity relationship (SAR) studies and lead optimization programs due to its modifiable scaffold.
• Biochemical Research: Serves as a reference standard or a probe compound in enzymatic and cellular assays.
• Organic Synthesis: Utilized in cross-coupling reactions (e.g., Suzuki, Buchwald-Hartwig) to introduce complex indole-based architectures.
• Contract Research & Manufacturing (CRAM): Supplied to organizations specializing in custom synthesis and process development for clinical candidates.

Basic Information

Product Name	1-Benzoyl-6-Bromo-7-Azaindole
CAS No.	143468-12-6
Molecular Formula	C₁₈H₁₁BrN₂O
Molecular Weight	351.20 g/mol
Synonyms	6-Bromo-1-benzoyl-1H-pyrrolo[2,3-b]pyridine; 6-Bromo-1H-pyrrolo[2,3-b]pyridin-1-yl(phenyl)methanone; 1-Benzoyl-6-bromo-1H-pyrrolo[2,3-b]pyridine; 6-Bromo-1-benzoyl-7-azaindole; 1-Benzoyl-6-bromo-7-aza-indole; 143468-12-6; 6-Bromo-1-benzoyl-pyrrolo[2,3-b]pyridine
EINECS	Contact for details

Quality Control

Our 1-Benzoyl-6-Bromo-7-Azaindole is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our commitment to cGMP principles ensures a reliable supply for research and development applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from incompatible materials. For long-term storage, consider storage under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	< 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.