Description

(8R,9Z,12Z)-8-Hydroperoxyoctadeca-9,12-Dienoic Acid is a specific hydroperoxy derivative of linoleic acid, a key intermediate in the biosynthesis of oxylipins and other bioactive lipid mediators. This compound matters for its role as a precursor in the study of lipid peroxidation pathways, enzymatic oxidation processes, and the development of signaling molecules in biological systems. It is needed by researchers and manufacturers in the pharmaceutical, nutraceutical, and advanced biochemical sectors for analytical standards, reference materials, and specialized synthesis.

Application

• Biochemical Research: Critical as a reference standard and intermediate for studying lipoxygenase pathways, lipid peroxidation mechanisms, and oxylipin biosynthesis.
• Pharmaceutical Development: Used as a precursor in the synthesis of more complex bioactive lipid mediators and eicosanoids for therapeutic research.
• Analytical Chemistry: Serves as a high-purity standard for HPLC, GC-MS, and other analytical methods to quantify lipid oxidation products in biological and food samples.
• Nutraceutical & Cosmetic Science: Investigated for its role in skin biology and inflammatory responses, supporting R&D in advanced cosmetic and health supplement formulations.
• Food Science: Employed in research to understand and control oxidative rancidity in lipids and oils, aiding in food preservation and quality assurance studies.

Basic Information

Product Name	(8R,9Z,12Z)-8-Hydroperoxyoctadeca-9,12-Dienoic Acid
CAS No.	143343-95-7
Molecular Formula	C18H32O4
Molecular Weight	312.44 g/mol
Synonyms	8(R)-HPODE; (8R)-HPODE; 8R-Hydroperoxy-9Z,12Z-octadecadienoic acid; 8(R)-Hydroperoxylinoleic acid; Linoleic acid 8R-hydroperoxide; 8-HPODE; 8-Hydroperoxy-cis-9,cis-12-octadecadienoic acid (8R); 9,12-Octadecadienoic acid, 8-hydroperoxy-, (8R,9Z,12Z)-
EINECS	Contact for details

Quality Control

Our (8R,9Z,12Z)-8-Hydroperoxyoctadeca-9,12-Dienoic Acid is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC purity analysis and spectroscopic identification, to ensure it meets the high standards required for research and development. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and stability is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below under an inert atmosphere (e.g., nitrogen or argon) to minimize degradation. For long-term storage, keep desiccated. Allow the sealed container to reach ambient temperature before opening to prevent condensation and moisture ingress.

Specification

Item	Specification
Appearance	Colorless to pale yellow viscous oil or solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 95%
Related Substances (HPLC)	Total impurities ≤ 5.0%
Solubility	Soluble in ethanol, methanol, DMSO; insoluble in water

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.