Description

Exo-8-Azabicyclo[3.2.1]Octan-2-Ol is a high-purity, advanced pharmaceutical intermediate characterized by its unique bridged bicyclic structure. This compound is of significant commercial importance as a key chiral building block in the synthesis of complex active pharmaceutical ingredients (APIs). It is primarily utilized by research institutions and manufacturers in the pharmaceutical and fine chemical industries for the development of new therapeutic agents.

Application

• Pharmaceutical Intermediate: Serves as a critical chiral synthon in the multi-step synthesis of novel drug candidates, particularly those targeting the central nervous system.
• Asymmetric Synthesis: Used as a precursor or catalyst ligand in stereoselective chemical reactions to produce enantiomerically pure compounds.
• Medicinal Chemistry Research: Employed in lead optimization and structure-activity relationship (SAR) studies during drug discovery programs.
• Fine Chemical Production: Acts as a building block for the manufacture of specialty chemicals with complex molecular architectures.
• Academic & Contract Research: Supplied to universities and CROs (Contract Research Organizations) for methodological development and chemical biology studies.

Basic Information

Product Name	Exo-8-Azabicyclo[3.2.1]Octan-2-Ol
CAS No.	143343-43-5
Molecular Formula	C7H13NO
Molecular Weight	127.18 g/mol
Synonyms	8-Azabicyclo[3.2.1]octan-2-ol, exo-; exo-2-Hydroxy-8-azabicyclo[3.2.1]octane; Tropan-2-ol, 8-aza-, exo-; (1R,2R,5S)-8-Azabicyclo[3.2.1]octan-2-ol; (exo)-8-Azabicyclo[3.2.1]octan-2-ol; 8-Azanortropan-2-ol; Nortropine
EINECS	Contact for details

Quality Control

Our Exo-8-Azabicyclo[3.2.1]Octan-2-Ol is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity assessment, to ensure it meets the high standards required for pharmaceutical R&D and production. Certificates of Analysis (COA) with detailed chromatographic data (HPLC/GC) are provided for every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). The product is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere for long-term storage to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.