Description

8-Fluoro-3,4-Dihydro-1H Quinolin-2-One is a high-purity fluorinated heterocyclic building block of significant interest in advanced organic synthesis. This compound matters as a versatile intermediate for constructing complex molecular architectures, particularly in the development of novel active pharmaceutical ingredients (APIs). Pharmaceutical R&D and fine chemical synthesis laboratories need it for creating potential drug candidates targeting a range of therapeutic areas.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of new drug molecules, particularly for central nervous system (CNS) and oncology targets.
• Agrochemical Synthesis: Used in the creation of advanced fluorinated pesticides and herbicides, where the fluorine atom can enhance biological activity and stability.
• Material Science Research: Serves as a precursor for developing novel organic electronic materials and liquid crystals due to its rigid, fused-ring structure.
• Academic & Industrial R&D: Employed in methodological studies and as a building block for constructing complex heterocyclic libraries in combinatorial chemistry.
• Fluorine Chemistry: A valuable substrate for studying fluorination reactions and the effects of fluorine substitution on chemical reactivity and physical properties.

Basic Information

Product Name	8-Fluoro-3,4-Dihydro-1H Quinolin-2-One
CAS No.	143268-79-5
Molecular Formula	C9H8FNO
Molecular Weight	165.17 g/mol
Synonyms	8-Fluoro-1,2,3,4-tetrahydroquinolin-2-one; 8-Fluoro-3,4-dihydro-2(1H)-quinolinone; 8-Fluoro-1,2,3,4-tetrahydro-2-quinolone; 8-Fluoro-2-oxo-1,2,3,4-tetrahydroquinoline; 8-Fluorotetrahydro-2-quinolone; 8-Fluoro-3,4-dihydrocarbostyril; 8-Fluoro-2-quinolone, tetrahydro-; 143268-79-5
EINECS	Contact for details

Quality Control

Our 8-Fluoro-3,4-Dihydro-1H Quinolin-2-One is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via NMR and mass spectrometry, to ensure it meets the high standards required for research and development applications. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.