Description

1-Boc-Piperazine Acetate is a high-purity, protected piperazine derivative widely used as a critical building block in organic synthesis. This compound is essential for the efficient and selective introduction of the piperazine moiety into complex molecular architectures, particularly in pharmaceutical research and development. It is a key intermediate for medicinal chemists and process R&D teams working on active pharmaceutical ingredients (APIs), especially in the areas of central nervous system (CNS) drugs, antivirals, and other therapeutic agents.

Application

• Pharmaceutical Intermediate: A crucial building block for synthesizing drug candidates containing the piperazine pharmacophore.
• API Synthesis: Used in the research, development, and scale-up production of various Active Pharmaceutical Ingredients (APIs).
• Peptide Mimetics & Modifications: Serves as a protected amine component for creating peptide-like structures and modifying peptide backbones.
• Ligand & Catalyst Development: Employed in the synthesis of novel ligands for catalysis and metal complexation studies.
• Chemical Biology Probes: Utilized as a scaffold for developing molecular probes and tool compounds in biochemical research.
• Custom Synthesis & Contract Manufacturing: A fundamental starting material for custom synthesis projects in fine chemical and CDMO (Contract Development and Manufacturing Organization) facilities.

Basic Information

Product Name	1-Boc-Piperazine Acetate
CAS No.	143238-38-4
Molecular Formula	C11H22N2O4
Molecular Weight	246.31 g/mol
Synonyms	1-Boc-piperazine acetate; tert-Butyl 4-piperazinecarboxylate acetate; 1-(tert-Butoxycarbonyl)piperazine acetate; Piperazine, 1-(1,1-dimethylethoxy)carbonyl-, acetate (1:1); 1-Boc-piperazine acetic acid salt; N-Boc-piperazine acetate; Boc-Pip-OH•AcOH; 1-N-Boc-piperazine acetate salt
EINECS	Contact for details

Quality Control

Our 1-Boc-Piperazine Acetate is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity suitable for research and pharmaceutical applications. Each lot undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry. A Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); keep the container tightly sealed when not in use to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Water Content (KF)	≤1.0%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.