Description

2-(Bromomethyl)-4,6-Difluorobenzothiazole is a high-value, multi-functional benzothiazole derivative, serving as a critical synthetic intermediate in advanced organic chemistry. Its molecular structure, featuring both a reactive bromomethyl group and fluorine substituents, makes it an essential building block for constructing complex heterocyclic systems. This compound is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders, inflammation, and oncology.
• Agrochemical Synthesis: Used in the development of next-generation herbicides, fungicides, and insecticides, leveraging the benzothiazole core for bioactivity.
• Material Science Research: Building block for creating advanced organic electronic materials, such as OLED (Organic Light-Emitting Diode) emitters and charge transport materials.
• Ligand and Catalyst Development: Serves as a starting point for synthesizing specialized ligands used in transition metal catalysis and coordination chemistry.
• Fluorescent Probe Synthesis: Utilized in the design and manufacture of fluorescent dyes and molecular probes for biochemical sensing and imaging.
• Custom Chemical Synthesis: Employed by contract research organizations (CROs) and custom synthesis facilities for client-specific projects requiring functionalized benzothiazoles.

Basic Information

Product Name	2-(Bromomethyl)-4,6-Difluorobenzothiazole
CAS No.	143163-73-9
Molecular Formula	C8H4BrF2NS
Molecular Weight	264.09 g/mol
Synonyms	4,6-Difluoro-2-(bromomethyl)benzothiazole; 2-Bromomethyl-4,6-difluorobenzothiazole; 4,6-Difluoro-2-(bromomethyl)-1,3-benzothiazole; 2-(Bromomethyl)-4,6-difluoro-1,3-benzothiazole; 1,3-Benzothiazole, 2-(bromomethyl)-4,6-difluoro-; 143163-73-9; 4,6-Difluoro-2-bromomethylbenzothiazole
EINECS	Contact for details

Quality Control

Every batch of 2-(Bromomethyl)-4,6-Difluorobenzothiazole is manufactured and tested under a strict quality management system. We provide comprehensive analytical data to ensure the product meets the high-purity standards required for research and scale-up applications. A detailed Certificate of Analysis (COA) is supplied with each shipment, confirming identity, purity, and impurity profiles as determined by advanced chromatographic and spectroscopic methods.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.