Description

2,5-Diazabicyclo[2.2.1]Heptane, 6-Methyl-2-(Trifluoroacetyl)-, (1R-Exo)- (9Ci) is a high-purity, chiral bicyclic diamine derivative featuring a trifluoroacetyl protecting group. This compound matters as a sophisticated pharmaceutical intermediate and chiral building block critical for the synthesis of complex active pharmaceutical ingredients (APIs). It is primarily needed by research institutions and manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors, where its unique stereochemistry enables the development of enantiomerically pure products.

Application

• Pharmaceutical Intermediate: Key chiral synthon for the development of novel APIs, particularly in antiviral, neurological, and oncological therapeutic areas.
• Asymmetric Catalyst Ligand Precursor: Used in the preparation of ligands for metal-catalyzed asymmetric synthesis, enhancing reaction selectivity and yield.
• Agrochemical Research: Serves as a building block for creating enantiomerically pure pesticides and herbicides with improved efficacy and environmental profiles.
• Advanced Material Synthesis: Employed in the research and development of specialty polymers and functional materials requiring precise molecular architecture.
• Process Chemistry & Scale-Up: Utilized in route scouting and optimization for the commercial-scale manufacturing of fine chemicals.
• Academic & Industrial R&D: A valuable tool for methodological studies in organic synthesis and medicinal chemistry.

Basic Information

Product Name	2,5-Diazabicyclo[2.2.1]Heptane, 6-Methyl-2-(Trifluoroacetyl)-, (1R-Exo)- (9Ci)
CAS No.	143004-11-9
Molecular Formula	C9H11F3N2O
Molecular Weight	220.19 g/mol
Synonyms	(1R-exo)-6-Methyl-2-(trifluoroacetyl)-2,5-diazabicyclo[2.2.1]heptane; (1R,4S)-6-Methyl-2-(trifluoroacetyl)-2,5-diazabicyclo[2.2.1]heptane; 2,5-Diazabicyclo[2.2.1]heptane, 6-methyl-2-(trifluoroacetyl)-, (1R,4S)-; exo-6-Methyl-2-(trifluoroacetyl)-2,5-diazabicyclo[2.2.1]heptane; (1R-exo)-6-Methyl-N-(trifluoroacetyl)-2,5-diazabicyclo[2.2.1]heptane; Trifluoroacetyl-protected exo-2,5-diazanorbornane derivative
EINECS	Contact for details

Quality Control

Our 2,5-Diazabicyclo[2.2.1]Heptane, 6-Methyl-2-(Trifluoroacetyl)-, (1R-Exo)- (9Ci) is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity verification by HPLC, to ensure it meets the high standards required for pharmaceutical R&D and production. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided and available upon request to support your regulatory and quality assurance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	< 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.