Description

4-Chloro-2-(Trifluoromethyl)Benzoic Acid is a high-value fluorinated aromatic building block characterized by its benzoic acid core substituted with both chloro and trifluoromethyl groups. This unique structure makes it a critical intermediate for synthesizing advanced molecules in life sciences and material chemistry. It is primarily sought after by research institutions and manufacturers in the pharmaceutical and agrochemical sectors for developing novel active ingredients.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of active pharmaceutical ingredients (APIs), particularly those targeting central nervous system (CNS) disorders, inflammation, and metabolic diseases.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides, where the trifluoromethyl group enhances biological activity and environmental stability.
• Liquid Crystal & OLED Material Precursor: Serves as a starting material for creating fluorinated compounds used in electronic displays and organic light-emitting diodes (OLEDs).
• Polymer & Specialty Chemical Modifier: Incorporated into polymers to impart specific properties like chemical resistance, thermal stability, or unique surface characteristics.
• Organic Synthesis & Catalysis Research: A versatile reagent in academic and industrial R&D for constructing complex molecular architectures and exploring new catalytic processes.
• Dye & Pigment Intermediate: Used in the synthesis of specialized colorants and pigments for high-performance applications.

Basic Information

Product Name	4-Chloro-2-(Trifluoromethyl)Benzoic Acid
CAS No.	142994-09-0
Molecular Formula	C8H4ClF3O2
Molecular Weight	224.56 g/mol
Synonyms	2-Trifluoromethyl-4-chlorobenzoic Acid; 4-Chloro-α,α,α-trifluoro-o-toluic Acid; 4-Chloro-2-(trifluoromethyl)benzenecarboxylic Acid; Benzoic acid, 4-chloro-2-(trifluoromethyl)-; 4-Chloro-α,α,α-trifluoro-2-methylbenzoic Acid; 4-Chloro-2-trifluoromethylbenzoic Acid
EINECS	Contact for details

Quality Control

Our production of 4-Chloro-2-(Trifluoromethyl)Benzoic Acid adheres to stringent quality management protocols to ensure batch-to-batch consistency and high purity. Each lot is analyzed using advanced techniques including HPLC, GC, and NMR to verify identity, potency, and impurity profiles. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment. We support cGMP standards for pharmaceutical applications and can accommodate custom purity requirements upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong bases, strong oxidizing agents, and sources of heat. For long-term storage, consider under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Melting Point	158°C - 162°C
Loss on Drying	≤0.5%
Residue on Ignition	≤0.1%
Heavy Metals (as Pb)	≤20 ppm
Related Substances (HPLC)	Individual impurity ≤0.5%; Total impurities ≤1.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.