Description

1-(4-Nitrophenyl)-5-(Trifluoromethyl)Pyrazole-4-Carboxylic Acid is a high-value, multi-functional heterocyclic building block essential for advanced organic synthesis. This compound matters for its unique molecular architecture, combining a pyrazole core with electron-withdrawing nitro and trifluoromethyl groups, which is critical for modulating the physicochemical properties of target molecules. It is primarily needed by R&D and production teams in the pharmaceutical and agrochemical industries for developing novel active ingredients, such as kinase inhibitors and herbicides.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of novel drug candidates, particularly for targeted therapies.
• Agrochemical Synthesis: Used in the creation of advanced pesticides and herbicides, leveraging its bioactive pyrazole scaffold.
• Chemical Research: Serves as a versatile building block in organic chemistry for constructing complex heterocyclic systems.
• Material Science: Potential precursor for the synthesis of specialty chemicals and functional materials.
• Bioconjugation & Probe Development: The carboxylic acid group allows for coupling reactions, useful in creating biochemical probes.

Basic Information

Product Name	1-(4-Nitrophenyl)-5-(Trifluoromethyl)Pyrazole-4-Carboxylic Acid
CAS No.	142818-03-9
Molecular Formula	C11H6F3N3O4
Molecular Weight	301.18 g/mol
Synonyms	4-Carboxy-1-(4-nitrophenyl)-5-(trifluoromethyl)-1H-pyrazole; 1-(p-Nitrophenyl)-5-(trifluoromethyl)-1H-pyrazole-4-carboxylic acid; 5-(Trifluoromethyl)-1-(4-nitrophenyl)-1H-pyrazole-4-carboxylic Acid; 1H-Pyrazole-4-carboxylic acid, 1-(4-nitrophenyl)-5-(trifluoromethyl)-; 142818-03-9; 1-(4-Nitrophenyl)-5-(trifluoromethyl)-4-pyrazolecarboxylic acid
EINECS	Contact for details

Quality Control

Our production of 1-(4-Nitrophenyl)-5-(Trifluoromethyl)Pyrazole-4-Carboxylic Acid adheres to stringent quality management protocols. Every batch undergoes comprehensive analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure consistency and compliance with customer specifications. Certificates of Analysis (COA) documenting all critical quality attributes are provided and available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to minimize exposure to atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.