Description

(1S,2S)-2-(4-Chlorophenyl)Cyclopropane-1-Carboxylic Acid is a high-purity chiral cyclopropane derivative, a crucial building block in modern organic synthesis. Its value lies in its defined stereochemistry and functional groups, enabling the precise construction of complex molecules. This intermediate is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries developing new active ingredients.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the synthesis of active pharmaceutical ingredients (APIs), particularly in antiviral, cardiovascular, and central nervous system (CNS) drug candidates.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides, where the cyclopropane moiety and chlorophenyl group contribute to biological activity.
• Ligand and Catalyst Development: Serves as a precursor for chiral ligands and organocatalysts used in asymmetric synthesis to control stereoselectivity.
• Material Science Research: Employed in the development of specialty polymers and advanced organic materials with specific structural properties.
• Chemical Biology Probes: Utilized as a scaffold for creating molecular probes to study enzyme mechanisms and biological pathways.

Basic Information

Product Name	(1S,2S)-2-(4-Chlorophenyl)Cyclopropane-1-Carboxylic Acid
CAS No.	142793-24-6
Molecular Formula	C10H9ClO2
Molecular Weight	196.63 g/mol
Synonyms	(1S,2S)-2-(4-Chlorophenyl)cyclopropanecarboxylic acid; (1S-cis)-2-(p-Chlorophenyl)cyclopropanecarboxylic Acid; trans-2-(4-Chlorophenyl)cyclopropanecarboxylic Acid (enantiomer); (1S,2S)-rel-2-(4-Chlorophenyl)cyclopropanecarboxylic Acid; 2-(4-Chlorophenyl)cyclopropane-1-carboxylic Acid (S,S-isomer); p-Chlorophenylcyclopropanecarboxylic Acid; A Chiral Cyclopropane Carboxylic Acid Derivative
EINECS	Contact for details

Quality Control

Our (1S,2S)-2-(4-Chlorophenyl)Cyclopropane-1-Carboxylic Acid is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral HPLC for enantiomeric purity and standard pharmacopeial identification methods, to ensure it meets the high standards required for advanced synthetic applications. A detailed Certificate of Analysis (COA) specifying purity, chiral excess, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong acids and organic solvents. The container must be kept tightly sealed to protect the contents from moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Individual impurity ≤ 0.5%, Total impurities ≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.