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3-Bromo-4-Chloro-8-Methoxyquinoline CAS NO 142781-92-8
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CAS No.:142781-92-8
Grade:Pharmacy Grade
Content:99.9%
Brand:Customizable
Packaging:Customizable
Description
3-Bromo-4-Chloro-8-Methoxyquinoline is a high-purity halogenated quinoline derivative, a crucial advanced intermediate in modern organic synthesis. Its value lies in its unique substitution pattern, which provides a versatile scaffold for constructing complex molecules with targeted biological activity. This compound is primarily sought by research and development teams in the pharmaceutical and agrochemical industries for use in medicinal chemistry and the synthesis of novel active ingredients.
Application
- Pharmaceutical Intermediate: A key building block in the research and synthesis of novel drug candidates, particularly in the development of antimicrobial, anticancer, and anti-inflammatory agents.
- Agrochemical Research: Serves as a core structure for developing new pesticides, herbicides, and fungicides due to the bioactive nature of the quinoline core.
- Material Science Precursor: Used in the synthesis of organic ligands for catalysis and in the development of advanced organic electronic materials.
- Chemical Synthesis Reagent: Employed in cross-coupling reactions (e.g., Suzuki, Buchwald-Hartwig) and as a substrate for further functionalization to create diverse chemical libraries.
- Academic & Institutional Research: Utilized in universities and research institutes for methodological studies and exploring new chemical transformations.
Basic Information
| Product Name | 3-Bromo-4-Chloro-8-Methoxyquinoline |
| CAS No. | 142781-92-8 |
| Molecular Formula | C₁₀H₇BrClNO |
| Molecular Weight | 272.53 g/mol |
| Synonyms | 8-Methoxy-3-bromo-4-chloroquinoline; 4-Chloro-3-bromo-8-methoxyquinoline; 3-Bromo-4-chloro-8-methoxy-quinoline; Quinoline, 3-bromo-4-chloro-8-methoxy-; 142781-92-8; BCMQ |
| EINECS | Contact for details |
Quality Control
Our 3-Bromo-4-Chloro-8-Methoxyquinoline is manufactured under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and GC-MS, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with every shipment, confirming it meets the agreed specifications for research and commercial use.
Storage
Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat and incompatible materials.
Specification
| Item | Specification |
|---|---|
| Appearance | White to off-white crystalline powder |
| Identification (IR) | Conforms to structure |
| Identification (HPLC) | Retention time matches reference standard |
| Purity (HPLC) | ≥ 97.0% |
| Water Content (KF) | ≤ 0.5% |
| Residue on Ignition | ≤ 0.1% |
Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.
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