Description

5-Nitro-8-(Piperidin-1-Yl)Quinoline is a specialized heterocyclic organic compound that serves as a crucial synthetic intermediate and building block in advanced chemical research and development. Its unique molecular architecture, featuring a quinoline core substituted with a nitro group and a piperidine moiety, makes it a valuable scaffold for creating novel compounds with targeted properties. This high-purity intermediate is primarily sought by research chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries for applications in medicinal chemistry, ligand synthesis, and the development of functional materials.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of potential drug candidates, particularly for targeting various biological receptors.
• Agrochemical Research: Used in the development of novel active ingredients for crop protection and pest management.
• Coordination Chemistry: Acts as a ligand precursor for the synthesis of metal complexes in catalysis and material science.
• Organic Synthesis: A versatile intermediate for constructing more complex nitrogen-containing heterocycles and fine chemicals.
• Material Science: Investigated for the development of organic semiconductors, fluorescent probes, or photoactive materials.
• Academic & Industrial R&D: Essential for fundamental research in synthetic methodology and structure-activity relationship (SAR) studies.

Basic Information

Product Name	5-Nitro-8-(Piperidin-1-Yl)Quinoline
CAS No.	142315-99-9
Molecular Formula	C14H15N3O2
Molecular Weight	257.29 g/mol
Synonyms	8-(1-Piperidinyl)-5-nitroquinoline; 5-Nitro-8-piperidin-1-ylquinoline; Quinoline, 5-nitro-8-(1-piperidinyl)-; 5-Nitro-8-piperidinoquinoline; 142315-99-9; 8-Piperidin-1-yl-5-nitroquinoline; 5-Nitro-8-(1-piperazinyl)quinoline (related); 5-NO2-8-Pip-Quinoline
EINECS	Contact for details

Quality Control

Our 5-Nitro-8-(Piperidin-1-Yl)Quinoline is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including HPLC for purity determination, NMR and IR for structural confirmation, and residual solvent analysis. We provide a detailed Certificate of Analysis (COA) with every shipment, documenting all critical quality attributes. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring reliability for your most demanding R&D and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep the container tightly sealed to protect from moisture. Store away from incompatible materials.

Specification

Item	Specification
Appearance	Yellow to orange crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 1.0%
Total Impurities (HPLC)	≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.