Description

1-Azaspiro[4.5]Decane-2,8-Dione, 1-Methyl- is a high-purity, specialized heterocyclic building block of significant interest in advanced organic synthesis. Its unique spirocyclic and diketone structure makes it a valuable intermediate for constructing complex molecular architectures. This compound is primarily sought by research and development teams in the pharmaceutical and agrochemical industries for applications in medicinal chemistry and novel active ingredient discovery.

Application

• Pharmaceutical Intermediate: A key synthon for the research and development of new active pharmaceutical ingredients (APIs), particularly those targeting central nervous system (CNS) disorders.
• Medicinal Chemistry Scaffold: Used in combinatorial chemistry and high-throughput screening libraries to explore novel bioactive compounds.
• Agrochemical Research: Serves as a building block in the synthesis of novel herbicides, fungicides, or insecticides with potential new modes of action.
• Organic Synthesis Reagent: Employed in academic and industrial R&D for constructing complex spirocyclic and heterocyclic compounds.
• Ligand and Catalyst Development: Potential precursor for creating novel chiral ligands or organocatalysts used in asymmetric synthesis.

Basic Information

Product Name	1-Azaspiro[4.5]Decane-2,8-Dione, 1-Methyl-
CAS No.	142283-66-7
Molecular Formula	C10H15NO2
Molecular Weight	181.23 g/mol
Synonyms	1-Methyl-1-azaspiro[4.5]decane-2,8-dione; 1-Methyl-2,8-dioxo-1-azaspiro[4.5]decane; 1-Methyl-1-azaspiro[4.5]decane-2,8-dione; 1-Methyl-1-aza-spiro[4.5]decane-2,8-dione; 1-Methyl-2,8-diazaspiro[4.5]decane-3,9-dione (incorrect but common misnomer); Spirocyclic diketone intermediate; Methyl azaspirodecandione
EINECS	Contact for details

Quality Control

Our 1-Azaspiro[4.5]Decane-2,8-Dione, 1-Methyl- is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity for research applications. We provide comprehensive analytical data including HPLC purity, NMR, and mass spectrometry confirmation. A Certificate of Analysis (COA) detailing all specifications is available with every shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (typically 15-25°C). Keep away from incompatible materials. For long-term storage, consider inert atmosphere conditions to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	< 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.