Description

8-Fluoro-1,4-Dioxaspiro[4.5]Dec-7-Ene is a high-value fluorinated spirocyclic building block of significant interest in advanced organic synthesis. Its unique structure, featuring a fluorine atom on an olefinic bridgehead, makes it a critical intermediate for constructing complex molecules with tailored properties. This compound is primarily sought after by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the development of novel active ingredients.

Application

• Pharmaceutical Intermediate: Serves as a key synthon in the research and development of new drug candidates, particularly for introducing fluorinated motifs to modulate bioavailability, metabolic stability, and binding affinity.
• Agrochemical Synthesis: Used in the creation of advanced pesticides and herbicides, where the fluorine atom and spirocyclic scaffold can enhance biological activity and environmental persistence profiles.
• Material Science Research: Employed as a monomer or precursor in the development of specialty polymers and advanced organic materials with specific electronic or surface properties.
• Fluorine Chemistry Studies: Acts as a model substrate in academic and industrial research to explore new fluorination reactions and the reactivity of fluorinated olefins in complex systems.
• Ligand and Catalyst Development: Utilized for synthesizing novel chiral or fluorinated ligands and organocatalysts for asymmetric synthesis applications.

Basic Information

Product Name	8-Fluoro-1,4-Dioxaspiro[4.5]Dec-7-Ene
CAS No.	142273-44-7
Molecular Formula	C9H11FO2
Molecular Weight	170.18 g/mol
Synonyms	8-Fluoro-1,4-dioxaspiro[4.5]dec-7-ene; 7-Fluoro-1,4-dioxaspiro[4.5]dec-7-ene; 8-Fluoro-1,4-dioxaspiro[4.5]dec-7-ene; Spiro[1,3-dioxolane-2,1'-cyclohex-4'-ene], 5'-fluoro-; 5'-Fluorospiro[1,3-dioxolane-2,1'-cyclohex-4'-ene]; 8-Fluoro-1,4-dioxaspiro[4.5]dec-7-ene (main IUPAC); Fluorinated spiroketal olefin
EINECS	Contact for details

Quality Control

Our 8-Fluoro-1,4-Dioxaspiro[4.5]Dec-7-Ene is produced under strict quality management protocols. Each batch undergoes comprehensive analytical characterization to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing results from GC, HPLC, NMR, and other relevant tests are provided to guarantee the material meets your specific research or development requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place. Due to its highly volatile nature, ensure containers are kept tightly sealed when not in use and stored at recommended room temperature (15-25°C). Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC/HPLC)	≥ 95.0% (Standard Grade)
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.