Description

(2S,3As,7As)- Octahydro-α,α-Diphenyl-1H-Indole-2-Methanol is a high-purity, stereochemically defined chiral indole derivative. This compound serves as a critical advanced pharmaceutical intermediate (API intermediate) for the synthesis of complex active ingredients. It is primarily needed by pharmaceutical R&D laboratories and fine chemical manufacturers engaged in developing novel therapeutic agents.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of proprietary drug candidates, particularly in central nervous system (CNS) and oncology research.
• Chiral Catalyst/Synthon: Utilized in asymmetric synthesis due to its defined stereocenters for constructing complex molecular architectures.
• Organic Synthesis Research: Serves as a versatile scaffold in academic and industrial research for developing new chemical entities.
• Reference Standard: Used as a high-purity analytical standard for method development and quality control in pharmaceutical analysis.

Basic Information

Product Name	(2S,3As,7As)-Octahydro-α,α-Diphenyl-1H-Indole-2-Methanol
CAS No.	142138-83-8
Molecular Formula	C23H27NO
Molecular Weight	333.47 g/mol
Synonyms	(2S,3aS,7aS)-Octahydro-α,α-diphenyl-1H-indole-2-methanol; (2S,3aS,7aS)-2-(Hydroxymethyl)octahydro-α,α-diphenyl-1H-indole; (2S,3aS,7aS)-α,α-Diphenyloctahydro-1H-indole-2-methanol; (2S,3aS,7aS)-rel-Octahydro-α,α-diphenyl-1H-indole-2-methanol; Diphenylindolemethanol derivative; Chiral indole alcohol intermediate.
EINECS	Contact for details

Quality Control

Our production of (2S,3As,7As)-Octahydro-α,α-Diphenyl-1H-Indole-2-Methanol adheres to stringent in-process controls to ensure batch-to-batch consistency and high chemical purity. Quality is verified through comprehensive analytical techniques including HPLC, chiral chromatography, and NMR. A Certificate of Analysis (COA) detailing identity, purity, and impurity profile is provided with each shipment to support your GMP-aligned or research applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to minimize exposure to atmospheric moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.