Description

2-(Ethoxycarbonyl)Isonicotinic Acid is a versatile pyridine derivative that serves as a crucial synthetic intermediate in advanced organic chemistry. This compound is valued for its bifunctional structure, which allows for selective modifications at both the carboxylic acid and ester moieties. It is primarily sought after by research and development chemists in the pharmaceutical and agrochemical industries for the synthesis of complex molecules, including active pharmaceutical ingredients (APIs) and novel crop protection agents.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of novel drug candidates, particularly those targeting neurological and infectious diseases.
• Agrochemical Synthesis: Used in the research and development of next-generation herbicides and insecticides.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands used in metal-catalyzed cross-coupling reactions.
• Material Science Research: Employed in the development of functional organic materials and metal-organic frameworks (MOFs).
• Custom Synthesis and Contract Manufacturing: A critical starting material for custom synthesis projects requiring specific pyridine-based architectures.
• Academic and Industrial R&D: Fundamental reagent for methodological studies in heterocyclic and medicinal chemistry.

Basic Information

Product Name	2-(Ethoxycarbonyl)Isonicotinic Acid
CAS No.	142074-49-5
Molecular Formula	C9H9NO4
Molecular Weight	195.17 g/mol
Synonyms	Ethyl 4-carboxypyridine-2-carboxylate; 2-Carboxyisonicotinic Acid Ethyl Ester; Isonicotinic Acid, 2-(ethoxycarbonyl)-; 4-Pyridinecarboxylic acid, 2-(ethoxycarbonyl)-; 2-Ethoxycarbonylisonicotinic acid; Ethyl 2,4-pyridinedicarboxylate; 2,4-Pyridinedicarboxylic acid, monoethyl ester
EINECS	Contact for details

Quality Control

Every batch of 2-(Ethoxycarbonyl)Isonicotinic Acid is manufactured and tested under a strict quality management system. Our products undergo rigorous analytical testing, including HPLC, NMR, and IR spectroscopy, to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing all test results is provided with each shipment to guarantee compliance with your research and production specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong acids and incompatible organic solvents. For long-term storage, consider storing under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.