Description

6-(Bromomethyl)-2-Methylquinoline is a versatile brominated quinoline derivative, a crucial building block in advanced organic synthesis. Its reactive bromomethyl group makes it an essential intermediate for constructing complex molecular architectures, particularly in pharmaceutical and materials science research. This compound is primarily sought after by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for creating novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of potential drug candidates, especially those with quinoline-based pharmacophores for anti-malarial, anti-cancer, or anti-inflammatory applications.
• Agrochemical Synthesis: Used in the development of novel fungicides, herbicides, and plant growth regulators where the quinoline scaffold is integral to biological activity.
• Ligand and Catalyst Preparation: Serves as a starting material for synthesizing specialized ligands used in transition metal catalysis and coordination chemistry.
• Material Science Research: Building block for creating organic semiconductors, light-emitting materials, or metal-organic frameworks (MOFs) due to its rigid, planar structure and functionalization site.
• Fluorescent Probe Development: Utilized in the design and synthesis of fluorescent markers and sensors for biochemical and diagnostic applications.
• Cross-Coupling Reactions: Acts as an electrophilic partner in various palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Heck) to form carbon-carbon bonds.

Basic Information

Product Name	6-(Bromomethyl)-2-Methylquinoline
CAS No.	141848-60-4
Molecular Formula	C₁₁H₁₀BrN
Molecular Weight	236.11 g/mol
Synonyms	2-Methyl-6-(bromomethyl)quinoline; 6-Bromomethyl-2-methylquinoline; Quinoline, 6-(bromomethyl)-2-methyl-; (2-Methylquinolin-6-yl)methyl bromide; 2-Methyl-6-quinolinylmethyl bromide
EINECS	Contact for details

Quality Control

Our 6-(Bromomethyl)-2-Methylquinoline is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and GC-MS, to ensure high chemical purity and identity confirmation. We provide Certificates of Analysis (COA) with detailed specifications for trace metals, residual solvents, and related substances, supporting cGMP and ISO standards for research and development use.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, containers should be amber-colored or stored in light-resistant packaging.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.