Description

4-(4-Chlorophenyl)Nicotinic Acid is a high-purity, versatile chemical intermediate featuring a chlorinated biphenyl core linked to a nicotinic acid moiety. This compound is valued for its role as a critical building block in the synthesis of advanced pharmaceutical compounds and agrochemicals, where its specific structure enables targeted molecular modifications. It is primarily sought after by research institutions, pharmaceutical development labs, and fine chemical manufacturers engaged in creating novel active ingredients.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system and metabolic disorders.
• Agrochemical Research: Serves as a foundational structure for developing new herbicides and fungicides with enhanced efficacy and selectivity.
• Ligand Synthesis: Used in organic and medicinal chemistry to create complex ligands for catalysis or receptor binding studies.
• Material Science: Investigated as a monomer or additive for creating specialized polymers with unique thermal or optical properties.
• Biochemical Research: Employed as a standard or probe in enzymatic and receptor-based assay development.

Basic Information

Product Name	4-(4-Chlorophenyl)Nicotinic Acid
CAS No.	141764-12-7
Molecular Formula	C12H8ClNO2
Molecular Weight	233.65 g/mol
Synonyms	4-(4-Chlorophenyl)pyridine-3-carboxylic acid; 3-Pyridinecarboxylic acid, 4-(4-chlorophenyl)-; 4-(p-Chlorophenyl)nicotinic acid; 4-(4-Chlorophenyl)-3-pyridinecarboxylic acid; 4-(4-Chlorophenyl)nicotinate; 141764-12-7; 4-(4-Chlorophenyl)nicotinic acid
EINECS	Contact for details

Quality Control

Our 4-(4-Chlorophenyl)Nicotinic Acid is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and stringent control of residual solvents and heavy metals. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment to ensure traceability and compliance with your research or production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to prevent moisture absorption, which may affect stability and handling properties.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Related Substances (HPLC)	Individual impurity ≤ 0.5%; Total impurities ≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.