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Sialyllewisxmethylglycoside CAS NO 141612-87-5


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CAS No.:141612-87-5

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

Sialyllewisxmethylglycoside CAS NO 141612-87-5 is a synthetic carbohydrate derivative, specifically a methyl glycoside of the sialyl Lewis X tetrasaccharide. This compound is a critical biochemical tool and reference standard for studying cell adhesion, inflammation, and metastasis processes. It is essential for researchers and developers in the pharmaceutical and biotechnology sectors who require high-purity, well-characterized ligands for glycan array screening, inhibitor development, and diagnostic assay calibration.

Application

  • Glycobiology Research: As a key reference standard for studying selectin-mediated cell adhesion and signaling pathways.
  • Drug Discovery: Serving as a core scaffold or competitive inhibitor in the development of anti-inflammatory and anti-metastatic therapeutics targeting selectins.
  • Diagnostic Development: Used in the calibration and validation of diagnostic assays and biosensors designed to detect specific carbohydrate-protein interactions.
  • Biomaterial Functionalization: For surface coating applications to create bioactive surfaces that mimic cell membrane properties for cell culture and study.
  • Enzymatic Synthesis Substrate: Acting as an acceptor substrate in enzymatic glycosylation reactions to synthesize more complex oligosaccharides.
  • Quality Control Standard: Employed as an analytical standard in HPLC, MS, or NMR for the quality control of related carbohydrate-based products.

Basic Information

Product Name Sialyllewisxmethylglycoside
CAS No. 141612-87-5
Molecular Formula C34H57NO23
Molecular Weight 847.81 g/mol
Synonyms α-Neu5Ac-(2→3)-β-D-Gal-(1→4)-[α-L-Fuc-(1→3)]-β-D-GlcNAc-OMe; Sialyl Lewis X Methyl Glycoside; SLex Methyl Glycoside; Neu5Acα2-3Galβ1-4(Fucα1-3)GlcNAcβ-OMe; 3'-Sialyl-N-acetyllactosamine Methyl Glycoside (fucosylated); CD15s Methyl Glycoside; Sialyl Lex Methyl Glycoside; Selectin Ligand Methyl Glycoside
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Quality Control

Our Sialyllewisxmethylglycoside is produced under strict quality management protocols to ensure batch-to-batch consistency and high purity, suitable for sensitive research applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity confirmation, and impurity profiles. We adhere to ISO 9001 quality standards, and our analytical methods are validated to meet the rigorous requirements of the pharmaceutical and life science industries.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. This product is hygroscopic (moisture-sensitive) and light-sensitive. For long-term storage, consider desiccation and storage under an inert atmosphere to maintain stability.

Specification

Item Specification
Appearance White to off-white powder
Identification (HPLC) Conforms to reference standard
Identification (NMR) Conforms to structure
Purity (HPLC) ≥ 95.0%
Water Content (KF) ≤ 5.0%
Residual Solvents (GC) Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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