Description

Tetra(2-Acetamido-2-Deoxy-Glucopyranosyl)Triphosphate 4-Nitrophenyl is a specialized nucleotide sugar derivative, a key biochemical building block for enzymatic synthesis and research. This compound is critical for studying and manipulating glycosylation pathways, which are fundamental to cellular communication, protein function, and drug development. It is primarily required by research institutions, pharmaceutical developers, and biotechnology companies engaged in advanced glycobiology, enzymology, and the synthesis of complex carbohydrates.

Application

• Glycobiology Research: As a high-energy sugar nucleotide donor for in vitro enzymatic synthesis of oligosaccharides and glycoconjugates.
• Enzyme Substrate & Assay Development: Used as a specific substrate for glycosyltransferases to study enzyme kinetics, inhibition, and mechanism of action.
• Pharmaceutical R&D: A crucial intermediate in the development of carbohydrate-based therapeutics, including vaccines, antibiotics, and anti-cancer agents.
• Diagnostic Reagent Manufacturing: Employed in the production of diagnostic kits and reagents that detect specific glycosyltransferase activities or carbohydrate structures.
• Biocatalysis & Synthetic Biology: Serves as a building block in engineered metabolic pathways for the production of valuable glycosylated natural products.
• Academic Research: Fundamental tool for investigating the role of specific glycosylation patterns in cell signaling, immune response, and disease pathology.

Basic Information

Product Name	Tetra(2-Acetamido-2-Deoxy-Glucopyranosyl)Triphosphate 4-Nitrophenyl
CAS No.	141334-39-6
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	Tetra-N-acetylchitotetraose-1,4-bisphosphate 4-nitrophenyl ester; P1,P4-Bis(4-nitrophenyl) P1,P4-di-β-D-N,N',N'',N'''-tetraacetylchitotetraosyl tetraphosphate; UDP-GlcNAc analog (tetramer); 4-Nitrophenyl tetra-N-acetyl-β-chitotetraosyl triphosphate; Glycosyl triphosphate derivative; N,N',N'',N'''-Tetraacetylchitotetraose 1,4-bisphosphate 4-nitrophenyl ester; Enzymatic glycosylation donor substrate
EINECS	Contact for details

Quality Control

Our Tetra(2-Acetamido-2-Deoxy-Glucopyranosyl)Triphosphate 4-Nitrophenyl is produced and handled under strict quality protocols to ensure batch-to-batch consistency and reliability for sensitive research applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to ISO 9001 quality management principles, and our analytical methods, including HPLC and NMR, are validated to provide accurate specifications for our customers' critical work.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a desiccated environment. This compound is hygroscopic (moisture-sensitive) and light-sensitive. For long-term stability, store under an inert atmosphere. Allow the sealed container to reach room temperature before opening to prevent condensation and moisture ingress.

Specification

Item	Specification
Appearance	White to off-white powder or solid
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 95%
Water Content (KF)	≤ 2.0%
Solubility	Soluble in DMSO, DMF; sparingly soluble in water

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.