Description

Carbamic Acid, [(1S)-2-Amino-1-Methyl-2-Thioxoethyl]-, 1,1-Dimethylethyl Ester is a specialized chiral thiocarbamate derivative of significant interest in advanced organic synthesis. This compound serves as a critical building block for the development of novel pharmaceuticals and bioactive molecules, particularly those targeting specific enzymatic pathways. Its unique structure, featuring both amino and thioxo functional groups, makes it an essential intermediate for researchers and manufacturers in the pharmaceutical, agrochemical, and fine chemical industries who require high-purity, stereochemically defined precursors.

Application

• Pharmaceutical Intermediate: Key chiral synthon for the synthesis of protease inhibitors, enzyme modulators, and other active pharmaceutical ingredients (APIs).
• Agrochemical Research: Building block for developing novel herbicides, fungicides, and insecticides with targeted activity.
• Peptidomimetic Chemistry: Used in the design and synthesis of peptide analogs and mimetics for drug discovery programs.
• Chemical Biology Probes: Serves as a precursor for activity-based probes used to study enzyme function and mechanism.
• Asymmetric Synthesis: Employed as a chiral auxiliary or reagent in stereoselective organic transformations.
• Fine Chemical Production: Intermediate for manufacturing high-value specialty chemicals and custom synthesis projects.

Basic Information

Product Name	Carbamic Acid, [(1S)-2-Amino-1-Methyl-2-Thioxoethyl]-, 1,1-Dimethylethyl Ester
CAS No.	141041-86-3
Molecular Formula	C8H16N2O2S
Molecular Weight	204.29 g/mol
Synonyms	(S)-tert-Butyl (2-amino-1-methyl-2-thioxoethyl)carbamate; (S)-N-Boc-2-amino-2-thioisobutyramide; tert-Butyl N-[(1S)-2-amino-1-methyl-2-sulfanylidene-ethyl]carbamate; Boc-L-2-amino-2-thioisobutyramide; (S)-2-((tert-Butoxycarbonyl)amino)-2-thioisobutyramide; (1S)-2-((tert-Butoxycarbonyl)amino)-2-thioisobutyramide; tert-Butyl [(1S)-2-amino-1-methyl-2-thioxoethyl]carbamate
EINECS	Contact for details

Quality Control

Our production of Carbamic Acid, [(1S)-2-Amino-1-Methyl-2-Thioxoethyl]-, 1,1-Dimethylethyl Ester adheres to stringent quality protocols to ensure batch-to-batch consistency and high purity for research and manufacturing applications. All materials are characterized by advanced analytical techniques including HPLC, NMR, and chiral analysis. Certificates of Analysis (COA) detailing purity, enantiomeric excess, and impurity profiles are provided with each shipment. We support compliance with cGMP and ISO 9001 standards where required.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and light-sensitive; therefore, containers must be kept tightly sealed and desiccated after opening to prevent degradation. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Enantiomeric Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 10 ppm
Related Substances (HPLC)	Individual impurity ≤ 0.5%, Total impurities ≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.