Description

2-Methyl-8-Trifluoromethylquinolin-4(1H)-One is a high-value, fluorinated quinolinone derivative, serving as a critical advanced intermediate in modern synthetic chemistry. Its core value lies in the unique trifluoromethyl group, which imparts desirable properties like enhanced metabolic stability and lipophilicity to target molecules. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly for the development of novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key building block for synthesizing potential drug candidates, especially in medicinal chemistry programs targeting CNS disorders, anti-infectives, and oncology.
• Agrochemical Research: Used in the development of new-generation pesticides and herbicides, where the fluorine moiety can improve biological activity and environmental profile.
• Material Science Precursor: Acts as a precursor for organic electronic materials, such as charge-transport layers or light-emitting components, due to its conjugated quinolinone structure.
• Chemical Synthesis Scaffold: Serves as a versatile scaffold for constructing more complex heterocyclic compounds in academic and industrial R&D laboratories.
• Fluorine Chemistry Studies: Employed as a model compound for studying the reactivity and effects of the trifluoromethyl group in heteroaromatic systems.

Basic Information

Product Name	2-Methyl-8-Trifluoromethylquinolin-4(1H)-One
CAS No.	140908-88-9
Molecular Formula	C₁₁H₈F₃NO
Molecular Weight	227.18 g/mol
Synonyms	4-Hydroxy-2-methyl-8-(trifluoromethyl)quinoline; 8-Trifluoromethyl-2-methyl-4-quinolinol; 2-Methyl-8-(trifluoromethyl)-4(1H)-quinolinone; 2-Methyl-8-trifluoromethyl-4-hydroxyquinoline; 4-Quinolinol, 2-methyl-8-(trifluoromethyl)-; 2-Methyl-8-trifluoromethylquinolin-4-ol
EINECS	Contact for details

Quality Control

Our 2-Methyl-8-Trifluoromethylquinolin-4(1H)-One is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via IR and NMR spectroscopy, to ensure it meets the high standards required for research and development applications. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from incompatible materials. The container should be kept tightly sealed to protect from moisture.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.