Description

Rhenium-186 Hedp CAS NO 140709-07-5 is a radiopharmaceutical compound where the β-emitting radioisotope Rhenium-186 is complexed with HEDP (Hydroxyethylidene Diphosphonate). This product matters for its targeted therapeutic action in palliative care for bone pain associated with metastatic cancer. It is specifically needed by radiopharmacies, nuclear medicine departments, and clinical research organizations involved in developing and administering bone-seeking radiopharmaceuticals.

Application

• Palliative Treatment of Bone Metastases: Primary application for the relief of severe pain from skeletal metastases, particularly in prostate and breast cancer.
• Radionuclide Therapy: Used as a therapeutic agent in targeted internal radiotherapy due to the beta emission of Re-186.
• Clinical Research: Serves as a key material in oncology research for studying bone-targeting radiopharmaceuticals and their efficacy.
• Radiopharmaceutical Formulation: Essential raw material for specialized radiopharmacies compounding patient-specific doses.
• Nuclear Medicine Diagnostics/Therapeutics (Theranostics): Can be part of theranostic pairs when used with imaging isotopes for treatment planning and monitoring.

Basic Information

Product Name	Rhenium-186 Hedp
CAS No.	140709-07-5
Molecular Formula	C2H8O7P2Re
Molecular Weight	Contact for details
Synonyms	186Re-HEDP; Rhenium-186 HEDP Complex; Rhenium-186 Etidronate; 186Re-Hydroxyethylidene Diphosphonate; Re-186(Sn)HEDP; Rhenium-186 (Tin) HEDP; Therapeutic Rhenium-186 HEDP; [186Re]Re-HEDP
EINECS	Contact for details

Quality Control

Every batch of Rhenium-186 Hedp is manufactured and tested under strict radiopharmaceutical GMP (Good Manufacturing Practice) guidelines. Quality assurance includes rigorous testing for radionuclidic purity, radiochemical purity, specific activity, and sterility. A comprehensive Certificate of Analysis (COA) detailing all release specifications, including pH and endotoxin levels, is provided with each shipment to ensure compliance with clinical-grade standards.

Storage

Preserve in a tightly closed container, protected from light. This product is strictly light-sensitive and must be protected from all light exposure during storage and handling. Store at controlled room temperature as specified on the product label and COA. Follow all applicable radiation safety protocols for storage and disposal.

Specification

Item	Specification
Appearance	Clear, colorless to slightly yellow solution
Radionuclidic Identity (Gamma)	Complies
Radionuclidic Purity	≥ 99% (Re-186)
Radiochemical Purity (HPLC/TLC)	≥ 95%
Specific Activity	Contact for details
pH	5.0 - 7.0
Sterility Test	Sterile
Bacterial Endotoxins (LAL)	< 175 EU/Vial

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.