Description

α-Hydroxyfarnesylphosphonic Acid is a specialized organophosphorus compound featuring a farnesyl chain, a phosphonic acid group, and an α-hydroxy moiety. This unique structure makes it a valuable intermediate in the synthesis of bioactive molecules and a potential ligand for metal coordination chemistry. It is primarily sought by research and development teams in the pharmaceutical and agrochemical sectors for use in drug discovery programs and the development of novel enzyme inhibitors.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of prenylated compounds and potential therapeutics targeting specific enzymatic pathways.
• Biochemical Research: Used as a substrate analog or inhibitor in enzymatic studies, particularly for enzymes involved in isoprenoid and sterol biosynthesis.
• Agrochemical Development: Serves as a precursor for novel crop protection agents due to its structural similarity to natural isoprenoids.
• Chemical Biology Probe: Utilized to study protein prenylation and related cellular processes.
• Ligand Synthesis: The phosphonic acid and hydroxy groups allow for chelation, making it useful in creating metal-organic frameworks (MOFs) or catalysts.
• Material Science: Potential monomer or additive for creating specialized polymers with unique properties.

Basic Information

Product Name	α-Hydroxyfarnesylphosphonic Acid
CAS No.	140633-12-1
Molecular Formula	C₁₅H₃₁O₄P
Molecular Weight	306.38 g/mol
Synonyms	AHFPA; (2-Hydroxy-3,7,11-trimethyldodeca-2,6,10-trien-1-yl)phosphonic acid; 1-Hydroxy-2-(3,7,11-trimethyl-2,6,10-dodecatrienyl)phosphonic acid; α-Hydroxyfarnesylphosphonic acid; Farnesylphosphonic acid, α-hydroxy derivative; 2-Hydroxy-3,7,11-trimethyl-2,6,10-dodecatrienylphosphonic acid
EINECS	Contact for details

Quality Control

Our α-Hydroxyfarnesylphosphonic Acid is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing including HPLC for purity, NMR and IR for structural confirmation, and specific tests for residual solvents and moisture. Certificates of Analysis (COA) detailing all specifications are provided to ensure full traceability and compliance with your research or development requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere for long-term stability.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.