Description

D-Myo-Inositol 1,3,4-Trisphosphate Hexapotassium Salt is a high-purity, cell-permeant derivative of the critical second messenger inositol trisphosphate (IP3). This compound is essential for researchers investigating intracellular calcium signaling pathways, receptor-mediated signal transduction, and phospholipase C (PLC) activity. It is primarily used in biochemical research, pharmaceutical development, and cell biology studies where precise modulation of calcium release from endoplasmic reticulum stores is required.

Application

• Intracellular Calcium Signaling Research: Used as a tool compound to study IP3 receptor (IP3R) activation and the subsequent release of calcium ions (Ca²⁺) from intracellular stores.
• Phospholipase C (PLC) Pathway Analysis: Serves as a reference standard and active metabolite in assays designed to measure PLC activity and the production of inositol phosphates.
• Drug Discovery & Development: Employed in high-throughput screening (HTS) and target validation for diseases involving dysregulated calcium signaling, such as neurological disorders and cardiac conditions.
• Cell Biology & Physiology Studies: Applied in experiments to probe the role of IP3 in processes like muscle contraction, neurotransmitter release, and gene expression.
• Biochemical Reagent: Used in the preparation of calibration standards and in enzymatic studies related to inositol phosphate metabolism.

Basic Information

Product Name	D-Myo-Inositol 1,3,4-Trisphosphate Hexapotassium Salt
CAS No.	140385-74-6
Molecular Formula	C6H9K6O15P3
Molecular Weight	756.68 g/mol
Synonyms	Ins(1,3,4)P3 Hexapotassium Salt; D-myo-Inositol 1,3,4-trisphosphate K+ salt; Inositol 1,3,4-trisphosphate hexapotassium; IP3 (1,3,4) hexapotassium salt; 1D-myo-Inositol 1,3,4-trisphosphate potassium salt; myo-Inositol 1,3,4-trisphosphate hexapotassium salt; D-Ins(1,3,4)P3 K6
EINECS	Contact for details

Quality Control

Our D-Myo-Inositol 1,3,4-Trisphosphate Hexapotassium Salt is manufactured under strict quality systems to ensure batch-to-batch consistency and high chemical purity suitable for sensitive research applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles as determined by advanced analytical techniques including HPLC and NMR.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below. This product is hygroscopic (moisture-sensitive). Allow the vial to equilibrate to room temperature in a desiccator before opening to minimize moisture absorption.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 95%
Water Content (KF)	≤ 5.0%
Potassium Content	30.0% - 32.0%
pH (1% Solution)	6.0 - 8.0

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.