Description

8-Azapsoralen is a heterocyclic organic compound belonging to the psoralen family, characterized by the substitution of a carbon atom in the psoralen core with a nitrogen atom. This structural modification is of significant interest in medicinal chemistry and photobiology for developing novel photoactive agents and biochemical probes. It serves as a valuable synthetic intermediate and research chemical for pharmaceutical R&D, particularly in the study of photochemotherapy and DNA intercalation. The compound is identified by the CAS registry number 140366-15-0.

Application

• Pharmaceutical Research & Development: Key intermediate in the synthesis of novel photoactive drug candidates for investigating photodynamic therapy (PDT) and PUVA therapy for skin conditions.
• Biochemical Probes: Used in academic and industrial research to study mechanisms of DNA and RNA interaction, enzyme inhibition, and cellular photobiology.
• Organic Synthesis: Serves as a versatile building block for constructing complex heterocyclic frameworks and fused ring systems in medicinal chemistry.
• Material Science Research: Investigated for potential applications in developing organic light-emitting diodes (OLEDs) or photo-responsive materials due to its conjugated structure.
• Analytical Reference Standard: Employed as a high-purity standard in analytical laboratories for method development, validation, and quality control of related compounds.

Basic Information

Product Name	8-Azapsoralen
CAS No.	140366-15-0
Molecular Formula	C₁₁H₆N₂O₂
Molecular Weight	198.18 g/mol
Synonyms	8-Azapsoralen; 8-Aza-4,5',8-trimethylpsoralen; 8-Aza-TMP; 5H-Furo[3,2-g][1]benzopyran-5-one, 8-aza-4,9-dimethyl-; 4,9-Dimethyl-8-azafuro[3,2-g]chromen-5-one; 8-Aza-4,9-dimethylfuro[3,2-g]chromen-5-one; NSC 348948
EINECS	Contact for details

Quality Control

Our 8-Azapsoralen is manufactured under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and residual solvent analysis. We provide a detailed Certificate of Analysis (COA) with every shipment, ensuring traceability and compliance with your research or development specifications. Our commitment is to deliver high-purity, consistent quality materials to support critical R&D and production processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from heat sources and incompatible materials. Due to its light-sensitive nature (store away from light), prolonged exposure to direct light should be avoided.

Specification

Item	Specification
Appearance	Off-white to light yellow powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.