Description

6-Hydroxy-1,1-Dioxo-1L6-[1,4]Thiazepane-4-Carboxylic Acid tert-Butyl Ester is a high-purity, advanced pharmaceutical intermediate characterized by its unique thiazepane ring structure. This compound is critical for the synthesis of complex active pharmaceutical ingredients (APIs), particularly in the development of novel therapeutic agents. It is primarily sought after by research institutions and pharmaceutical manufacturers engaged in the development of new drugs, especially within the fields of neurology and metabolic disease research.

Application

• Pharmaceutical Intermediate: A key building block in the multi-step synthesis of novel drug candidates, particularly those targeting specific enzyme pathways.
• Protease Inhibitor Research: Used in the research and development of protease inhibitors due to its structural similarity to transition-state analogs.
• Chemical Biology Probes: Serves as a precursor for creating specialized molecular probes to study biological mechanisms and protein interactions.
• Peptidomimetic Synthesis: Employed in the construction of peptidomimetics, which are molecules that mimic peptides but with enhanced stability and bioavailability.
• Medicinal Chemistry R&D: A valuable scaffold for medicinal chemists exploring new chemical entities (NCEs) and structure-activity relationships (SAR).
• Custom Synthesis: Used by contract research and manufacturing organizations (CROs/CMOs) for custom synthesis projects on behalf of pharmaceutical clients.

Basic Information

Product Name	6-Hydroxy-1,1-Dioxo-1L6-[1,4]Thiazepane-4-Carboxylic Acid tert-Butyl Ester
CAS No.	140217-83-0
Molecular Formula	C11H19NO5S
Molecular Weight	277.34 g/mol
Synonyms	tert-Butyl 6-hydroxy-1,1-dioxo-1,4-thiazepane-4-carboxylate; 1,4-Thiazepane-4-carboxylic acid, 6-hydroxy-1,1-dioxide, 1,1-dimethylethyl ester; 4-(tert-Butoxycarbonyl)-6-hydroxy-1,4-thiazepane 1,1-dioxide; 6-Hydroxy-1,1-dioxo-1,4-thiazepane-4-carboxylic acid tert-butyl ester; Boc-6-Hydroxy-1,4-thiazepane-1,1-dioxide; 140217-83-0
EINECS	Contact for details

Quality Control

Our 6-Hydroxy-1,1-Dioxo-1L6-[1,4]Thiazepane-4-Carboxylic Acid tert-Butyl Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for pharmaceutical R&D. Certificates of Analysis (COA) with detailed chromatographic data are provided for every shipment to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled under dry conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.