Description

n-Octyl 3,6-Di-o-(A-D-Mannopyranosyl)-B-D-Mannopyranoside is a high-purity, non-ionic glycolipid surfactant derived from mannose. This compound is valued for its ability to solubilize membrane proteins while maintaining their native structure and function, making it a critical reagent in structural biology and biochemistry. It is primarily used by research institutions and pharmaceutical companies engaged in membrane protein purification, crystallization, and biophysical analysis.

Application

• Membrane Protein Solubilization and Stabilization: Essential for extracting and stabilizing integral membrane proteins from cellular membranes for downstream analysis.
• Structural Biology: Used in the crystallization of membrane proteins for X-ray crystallography and cryo-electron microscopy (cryo-EM) studies.
• Biophysical Characterization: Employed in techniques such as surface plasmon resonance (SPR), isothermal titration calorimetry (ITC), and nuclear magnetic resonance (NMR) to study protein-ligand interactions.
• Drug Discovery Research: Facilitates the functional reconstitution of drug targets like G-protein-coupled receptors (GPCRs) and ion channels for high-throughput screening assays.
• Vaccine Development: Can be utilized as a mild detergent in the formulation and purification of viral envelope proteins.
• Diagnostic Assays: Serves as a gentle surfactant in immunoassay buffers to preserve antigen conformation and enhance assay sensitivity.

Basic Information

Product Name	n-Octyl 3,6-Di-o-(A-D-Mannopyranosyl)-B-D-Mannopyranoside
CAS No.	140147-36-0
Molecular Formula	C26H48O16
Molecular Weight	616.66 g/mol
Synonyms	Octyl 3,6-Di-O-α-D-mannopyranosyl-β-D-mannopyranoside; n-Octyl α-D-mannopyranosyl-(1→3)-[α-D-mannopyranosyl-(1→6)]-β-D-mannopyranoside; Glycolipid Surfactant ODM; Mannose-based Non-Ionic Detergent; Membrane Protein Solubilizer ODM; ODM Detergent; Octyl-Di-Mannoside; 1-Octyl 3,6-di-O-α-D-mannopyranosyl-β-D-mannopyranoside
EINECS	Contact for details

Quality Control

Our n-Octyl 3,6-Di-o-(A-D-Mannopyranosyl)-B-D-Mannopyranoside is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity assessment and NMR for structural confirmation, to ensure it meets the stringent requirements of life science research. A detailed Certificate of Analysis (COA) is provided with every shipment, guaranteeing traceability, consistency, and compliance with your research protocols.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. This product is hygroscopic (moisture-sensitive). Allow the vial to equilibrate to room temperature in a desiccator before opening to prevent condensation and moisture uptake.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 2.0%
Critical Micelle Concentration (CMC)	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.