Description

(1S,4S,5S)-4-Bromo-6-Oxabicyclo[3.2.1]Octan-7-One is a high-purity, chiral bicyclic lactone building block of significant interest in advanced organic synthesis. Its unique bridged oxabicyclo[3.2.1]octane scaffold, functionalized with a bromine atom, makes it a versatile precursor for constructing complex molecular architectures. This compound is primarily utilized by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and chiral intermediates.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the development of novel drug candidates, particularly in medicinal chemistry programs targeting central nervous system (CNS) disorders and anti-infective agents.
• Agrochemical Synthesis: Serves as a building block for creating advanced, stereochemically defined active ingredients for crop protection products.
• Asymmetric Catalysis Research: Used as a substrate or ligand precursor in the development and testing of new asymmetric catalytic reactions.
• Natural Product Synthesis: An important intermediate in the total synthesis of complex natural products containing bridged oxygen heterocycles.
• Material Science Research: Potential monomer or precursor for synthesizing specialized polymers with unique structural properties.
• Process Chemistry & Scale-Up: Employed in route scouting and optimization for the efficient, large-scale production of target molecules.

Basic Information

Product Name	(1S,4S,5S)-4-Bromo-6-Oxabicyclo[3.2.1]Octan-7-One
CAS No.	139893-81-5
Molecular Formula	C7H9BrO2
Molecular Weight	205.05 g/mol
Synonyms	(1S,4S,5S)-4-Bromo-6-oxabicyclo[3.2.1]octan-7-one; 4-Bromo-6-oxabicyclo[3.2.1]octan-7-one, (1S,4S,5S)-; (1S,4S,5S)-4-Bromo-6-oxabicyclo[3.2.1]octan-7-one; 4-Bromo-6-oxabicyclo[3.2.1]octan-7-one; Bicyclo[3.2.1]octan-7-one, 4-bromo-6-oxa-, (1S,4S,5S)-; Chiral 4-bromo lactone building block; SCHEMBL21833031
EINECS	Contact for details

Quality Control

Our (1S,4S,5S)-4-Bromo-6-Oxabicyclo[3.2.1]Octan-7-One is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including chiral purity verification, to ensure high chemical and stereochemical purity suitable for demanding synthetic applications. Certificates of Analysis (COA) with detailed chromatographic data (HPLC, GC) are provided to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place. For long-term storage, it is recommended to keep the material at 2-8°C under an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 98.0% ee
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.