Description

(E)-1-(6-Bromo-2-Hydroxy-4-Phenylquinolin-3-Yl)-3-(Furan-2-Yl)Prop-2-En-1-One is a high-purity, synthetic organic compound featuring a complex quinoline-furan hybrid structure, making it a valuable advanced pharmaceutical intermediate and key building block for medicinal chemistry research. Its unique molecular architecture, incorporating bromo, hydroxy, and phenyl substituents, provides versatile sites for further chemical modification. This compound is primarily utilized by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries for the synthesis of novel active molecules.

Application

• Pharmaceutical Intermediate: Serves as a critical precursor in the synthesis of potential drug candidates, particularly those targeting kinase inhibition or other biological pathways where the quinoline scaffold is relevant.
• Medicinal Chemistry Research: Used as a sophisticated building block for constructing compound libraries in high-throughput screening and structure-activity relationship (SAR) studies.
• Agrochemical Development: Acts as an intermediate in the research and development of new crop protection agents and pesticides.
• Material Science Precursor: Employed in the development of organic electronic materials, ligands for metal-organic frameworks (MOFs), or functional dyes due to its conjugated system.
• Chemical Biology Probe: Utilized in the design and synthesis of molecular probes for studying biological processes and target identification.
• Academic & Institutional Research: Supplied to universities and research institutes for fundamental studies in organic synthesis and heterocyclic chemistry.

Basic Information

Product Name	(E)-1-(6-Bromo-2-Hydroxy-4-Phenylquinolin-3-Yl)-3-(Furan-2-Yl)Prop-2-En-1-One
CAS No.	139888-27-0
Molecular Formula	C22H14BrNO3
Molecular Weight	420.26 g/mol
Synonyms	(E)-1-(6-Bromo-2-hydroxy-4-phenylquinolin-3-yl)-3-(furan-2-yl)prop-2-en-1-one; 3-(2-Furylacryloyl)-6-bromo-2-hydroxy-4-phenylquinoline; 6-Bromo-2-hydroxy-4-phenyl-3-[(1E)-3-(2-furanyl)-1-oxo-2-propen-1-yl]quinoline; 139888-27-0; (E)-1-(6-Bromo-2-Hydroxy-4-Phenyl-3-Quinolyl)-3-(2-Furyl)-2-Propen-1-One; 3-[(E)-3-(Furan-2-yl)acryloyl]-6-bromo-2-hydroxy-4-phenylquinoline
EINECS	Contact for details

Quality Control

Our production of (E)-1-(6-Bromo-2-Hydroxy-4-Phenylquinolin-3-Yl)-3-(Furan-2-Yl)Prop-2-En-1-One adheres to stringent quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with each shipment, documenting critical specifications such as assay purity and impurity profiles. Our commitment to cGMP principles ensures reliability for research and development applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). This compound is light-sensitive (store away from light) and may be hygroscopic (moisture-sensitive); therefore, containers should be kept sealed under an inert atmosphere if specified. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	Yellow to light brown crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0% (Area %)
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.