Description

3-Acetyl-6-Bromo-4-Phenylquinolin-2(1H)-One is a high-purity, advanced pharmaceutical intermediate characterized by its brominated quinolinone core structure. This compound matters for its critical role as a versatile building block in the synthesis of complex bioactive molecules, particularly in medicinal chemistry research and development. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries for creating novel compounds with potential therapeutic or agrochemical activity.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of novel drug candidates, particularly those targeting various enzyme systems.
• Medicinal Chemistry Research: Used as a scaffold for structure-activity relationship (SAR) studies to optimize biological activity and pharmacokinetic properties.
• Agrochemical Development: Employed in the research and synthesis of new active ingredients for crop protection products.
• Organic Synthesis Building Block: Utilized in complex multi-step organic syntheses due to its reactive acetyl and bromo functional groups.
• Chemical Biology Probes: Acts as a core structure for developing molecular probes to study biological pathways and target validation.
• Fine Chemical Production: Incorporated into the manufacture of specialty chemicals and high-value materials.

Basic Information

Product Name	3-Acetyl-6-Bromo-4-Phenylquinolin-2(1H)-One
CAS No.	139781-14-9
Molecular Formula	C₁₇H₁₂BrNO₂
Molecular Weight	342.19 g/mol
Synonyms	3-Acetyl-6-bromo-4-phenyl-1H-quinolin-2-one; 6-Bromo-3-acetyl-4-phenyl-1,2-dihydroquinolin-2-one; 3-Acetyl-6-bromo-4-phenyl-2(1H)-quinolinone; 2(1H)-Quinolinone, 3-acetyl-6-bromo-4-phenyl-; 139781-14-9; 3-Acetyl-6-bromo-4-phenylquinolin-2-ol (tautomer); 6-Bromo-3-acetyl-4-phenylquinolin-2(1H)-one
EINECS	Contact for details

Quality Control

Our 3-Acetyl-6-Bromo-4-Phenylquinolin-2(1H)-One is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our commitment to quality supports your research and development needs with reliable, high-purity material.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (typically 15-25°C). This material is light-sensitive (store away from light) and may be hygroscopic (moisture-sensitive). Keep away from incompatible materials. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 97.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.