Description

4,5-Dihydro-3H,3'H-Spiro[Furan-2,1'-Isobenzofuran] is a specialized spirocyclic organic compound with the CAS number 139697-84-0, serving as a valuable synthetic intermediate and building block in advanced organic chemistry. Its unique fused furan and isobenzofuran structure makes it a critical precursor for developing complex molecules with specific electronic and steric properties. This high-purity intermediate is essential for research and production in pharmaceutical development, agrochemical synthesis, and materials science.

Application

• Pharmaceutical Intermediate: Key building block for synthesizing novel active pharmaceutical ingredients (APIs), particularly in central nervous system (CNS) and antiviral drug research.
• Agrochemical Synthesis: Used in the development of advanced pesticides and herbicides, leveraging its spirocyclic framework for enhanced biological activity.
• Organic Light-Emitting Diode (OLED) Materials: Serves as a core structure for creating electron-transport materials and host materials in display technologies.
• Ligand and Catalyst Development: Utilized in organometallic chemistry to create novel chiral ligands and catalysts for asymmetric synthesis.
• Polymer and Resin Modifiers: Incorporated into specialty polymers to impart unique thermal stability or optical properties.
• Academic and R&D Laboratories: A crucial reagent for methodological studies in synthetic organic chemistry and the construction of complex natural product analogs.

Basic Information

Product Name	4,5-Dihydro-3H,3'H-Spiro[Furan-2,1'-Isobenzofuran]
CAS No.	139697-84-0
Molecular Formula	C12H12O2
Molecular Weight	188.22 g/mol
Synonyms	Spiro[isobenzofuran-1(3H),2'-[2,5]dihydrofuran]; 1,3-Dihydrospiro[isobenzofuran-1,2'-furan]; 3'H-Spiro[isobenzofuran-1,2'-furan]-3-one, dihydro-; Spiro[3H-2,1-benzoxafuran-1,2'-oxolane]; 139697-84-0; Spiro(dihydrofuran-2,1'-isobenzofuran); Dihydrospiro[furan-2,1'-isobenzofuran]
EINECS	Contact for details

Quality Control

Our 4,5-Dihydro-3H,3'H-Spiro[Furan-2,1'-Isobenzofuran] is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing key parameters such as identity, assay, and impurity profiles. Our quality management system adheres to cGMP guidelines where applicable, supporting its use in regulated research and development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flames. For long-term storage, consider an inert atmosphere to maintain product stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Related Substances (HPLC)	Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.