Description

6-Cyclopropyl-8,9-Difluoro-7-Methoxy-4-Oxo-4,6-Dihydro-2H-1L3-[1,3]Dioxino[5,6-C]Quinoline-2,2-Diyl Diacetate is a high-purity, advanced pharmaceutical intermediate with a complex heterocyclic structure. This compound is critical for the synthesis of next-generation fluoroquinolone antibiotics, offering a key building block for research and development. It is primarily required by pharmaceutical manufacturers and R&D laboratories engaged in the development of novel antimicrobial agents.

Application

• Pharmaceutical Intermediate: A key synthetic precursor in the production of advanced fluoroquinolone antibiotic APIs.
• Antimicrobial Research: Used in medicinal chemistry for the design and synthesis of new antibacterial compounds with improved efficacy.
• Process Chemistry: Serves as a critical intermediate in scale-up and optimization studies for commercial drug manufacturing.
• Chemical Reference Standard: Employed as a high-purity standard for analytical method development and quality control in pharmaceutical labs.
• Academic Research: Utilized in university and institutional research projects focused on heterocyclic chemistry and drug discovery.

Basic Information

Product Name	6-Cyclopropyl-8,9-Difluoro-7-Methoxy-4-Oxo-4,6-Dihydro-2H-1L3-[1,3]Dioxino[5,6-C]Quinoline-2,2-Diyl Diacetate
CAS No.	139693-52-0
Molecular Formula	C20H17F2NO7
Molecular Weight	421.35 g/mol
Synonyms	1-Cyclopropyl-6,7-difluoro-8-methoxy-4-oxo-1,4-dihydro-3-quinolinecarboxylic acid 2,2-diacetate; Difluoroquinolone Intermediate; 8,9-Difluoro-7-methoxy-6-cyclopropyl-4-oxo-4,6-dihydro-2H-1,3-dioxino[5,6-c]quinoline-2,2-diyl diacetate; Gatifloxacin Intermediate; AM-1155 Intermediate; (1-Cyclopropyl-6,7-difluoro-8-methoxy-4-oxo-1,4-dihydroquinoline-3-carboxylic acid) cyclic 2,2-diacetate; 139693-52-0; Quinolone Derivative 139693-52-0
EINECS	Contact for details

Quality Control

Our 6-Cyclopropyl-8,9-Difluoro-7-Methoxy-4-Oxo-4,6-Dihydro-2H-1L3-[1,3]Dioxino[5,6-C]Quinoline-2,2-Diyl Diacetate is manufactured under strict quality management systems. The product undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure high chemical purity and structural identity. Certificates of Analysis (COA) with batch-specific data are available upon request to support your regulatory and quality assurance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Any single impurity	≤ 0.5%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.