Description

2-Chloro-5-(Trifluoromethoxy)Phenol is a versatile halogenated phenolic intermediate of significant importance in advanced organic synthesis. Its unique structure, featuring both chloro and trifluoromethoxy substituents, makes it a critical building block for creating complex molecules with tailored properties. This compound is primarily sought after by research institutions and manufacturers in the agrochemical and pharmaceutical sectors for the development of novel active ingredients.

Application

• Agrochemical Intermediate: A key precursor in the synthesis of modern herbicides, fungicides, and insecticides, where the trifluoromethoxy group enhances biological activity and environmental stability.
• Pharmaceutical Building Block: Used in medicinal chemistry research for constructing pharmacologically active molecules, particularly in drug discovery programs targeting CNS and metabolic diseases.
• Liquid Crystal & OLED Material Synthesis: Serves as a starting material for creating specialized fluorinated compounds used in electronic displays and organic light-emitting diodes.
• Polymer & Resin Modification: Employed to introduce halogen and fluorine-containing side chains into polymers, improving their chemical resistance, thermal stability, and surface properties.
• Organic Synthesis Reagent: Utilized in cross-coupling reactions and as a protecting group or directing agent in complex multi-step synthetic routes.

Basic Information

Product Name	2-Chloro-5-(Trifluoromethoxy)Phenol
CAS No.	139625-85-7
Molecular Formula	C7H4ClF3O2
Molecular Weight	212.55 g/mol
Synonyms	2-Chloro-5-(trifluoromethoxy)phenol; Phenol, 2-chloro-5-(trifluoromethoxy)-; 2-Chloro-α,α,α-trifluoro-p-anisyl alcohol; 5-Chloro-2-hydroxybenzotrifluoride methyl ether derivative; 2-Chloro-5-(trifluoromethoxy)benzenol; 1-Chloro-4-hydroxy-2-(trifluoromethoxy)benzene; 2-Chloro-5-(trifluoromethoxy)phenol (CAS 139625-85-7)
EINECS	Contact for details

Quality Control

Our production of 2-Chloro-5-(Trifluoromethoxy)Phenol adheres to stringent quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistency. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with every shipment, supporting your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from strong oxidizing agents, strong bases, and sources of ignition. The container should be kept tightly sealed to minimize exposure to moisture and air.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.