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3-(Aminooxy)-2-Fluoropropanamine CAS NO 139526-94-6


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CAS No.:139526-94-6

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

3-(Aminooxy)-2-Fluoropropanamine is a specialized bifunctional organic compound featuring both an aminooxy and a primary amine group on a fluorinated propane backbone. This unique structure makes it a valuable high-purity building block for the synthesis of complex molecules, particularly in pharmaceutical research and advanced material science. It is primarily sought after by R&D chemists and process development scientists in the life sciences, agrochemical, and specialty chemical industries for creating novel drug candidates, ligands, and functional polymers.

Application

  • Pharmaceutical Intermediate: Key synthon for the development of active pharmaceutical ingredients (APIs), especially in oncology and antiviral research.
  • Bioconjugation & Linker Chemistry: Used to create cleavable linkers for antibody-drug conjugates (ADCs) or to attach payloads to targeting molecules via its aminooxy group.
  • Ligand Synthesis for Catalysis: Serves as a precursor for constructing sophisticated ligands used in asymmetric catalysis and metal-organic frameworks (MOFs).
  • Polymer Modification: Imparts functional groups to polymer chains for creating specialty materials with tailored surface properties or reactivity.
  • Agrochemical Research: Building block for novel herbicides, fungicides, or plant growth regulators that require specific fluorine-containing motifs.
  • Crosslinking Agent: Potential use in formulating crosslinked hydrogels or resins for biomedical and industrial applications.

Basic Information

Product Name 3-(Aminooxy)-2-Fluoropropanamine
CAS No. 139526-94-6
Molecular Formula C₃H₉FN₂O
Molecular Weight 108.12 g/mol
Synonyms 2-Fluoro-3-(aminooxy)propan-1-amine; 1-Amino-3-(aminooxy)-2-fluoropropane; 3-Aminooxy-2-fluoropropylamine; 2-Fluoropropane-1,3-diamine, O-ether; 139526-94-6; Aminooxy-fluoropropanamine; 2-Fluoro-3-aminoxypropylamine
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Quality Control

We supply 3-(Aminooxy)-2-Fluoropropanamine in high-purity grades suitable for research and development. Our products undergo rigorous quality testing to ensure compliance with industry standards, including analysis by NMR, HPLC, and MS. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each batch to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); therefore, containers must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item Specification
Appearance Colorless to pale yellow liquid
Identification (NMR) Conforms to structure
Purity (HPLC) ≥ 95.0%
Water Content (KF) ≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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