Description

2,2-Difluoro-n-Methylethanamine Hydrochloride CAS NO 139364-36-6 is a specialized organofluorine building block in the form of a hydrochloride salt, offering enhanced stability and handling properties. This compound is valued for its role in introducing a difluoroethylamine moiety into complex molecular architectures, a key modification in modern medicinal chemistry. It is primarily sought by research and development teams in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients.

Application

• Pharmaceutical Intermediate: A critical building block for the synthesis of active pharmaceutical ingredients (APIs), particularly in developing fluorinated drug candidates for oncology, CNS disorders, and metabolic diseases.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides, where the fluorine atoms can enhance biological activity, stability, and environmental profile.
• Chemical Biology & Proteomics: Serves as a reagent for labeling and modifying biomolecules, enabling studies on protein function and interaction.
• Material Science Research: Employed in the development of novel fluorinated polymers and functional materials with specific surface properties.
• Custom Synthesis & Contract Manufacturing: A key starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving the global life sciences market.

Basic Information

Product Name	2,2-Difluoro-n-Methylethanamine Hydrochloride
CAS No.	139364-36-6
Molecular Formula	C₃H₈ClF₂N
Molecular Weight	131.55 g/mol
Synonyms	N-Methyl-2,2-difluoroethanamine Hydrochloride; 2,2-Difluoro-N-methylethanamine HCl; 1,1-Difluoro-N-methylethanaminium Chloride; 2,2-Difluoroethyl(methyl)amine Hydrochloride; N-Methyl-2,2-difluoroethylamine Hydrochloride; (2,2-Difluoroethyl)(methyl)amine Hydrochloride; 139364-36-6; 2,2-Difluoro-N-methylethylamine Hydrochloride
EINECS	Contact for details

Quality Control

Our 2,2-Difluoro-n-Methylethanamine Hydrochloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation by NMR and IR spectroscopy, to ensure it meets the stringent requirements for advanced synthetic applications. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere or in a desiccated environment after opening to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.