Description

Rebamipide is a gastroprotective agent and mucin secretagogue used primarily in pharmaceutical applications. This compound is valued for its role in promoting the healing of gastric ulcers and protecting the gastrointestinal mucosa. It is a critical active pharmaceutical ingredient (API) for manufacturers developing treatments for gastritis and gastric ulcers, serving the global pharmaceutical and research sectors.

Application

• Primary use as an Active Pharmaceutical Ingredient (API) in gastroprotective medications.
• Formulation of prescription drugs for the treatment and prevention of gastric ulcers and gastritis.
• Key component in ophthalmic solutions for the treatment of dry eye disease (keratoconjunctivitis sicca).
• Utilized in clinical and preclinical research studying gastrointestinal cytoprotection and mucosal defense mechanisms.
• Intermediate in the synthesis of novel pharmaceutical derivatives and prodrugs.
• Reference standard for analytical testing and quality control in pharmaceutical manufacturing.

Basic Information

Product Name	Rebamipide
CAS No.	139344-42-6
Molecular Formula	C19H15ClN2O4
Molecular Weight	370.79 g/mol
Synonyms	OPC-12759; 2-(4-Chlorobenzoylamino)-3-[2(1H)-quinolinon-4-yl]propionic Acid; Rebamipidum; Proamipide; Mucosta (brand name); Rebamipide API; 4-Quinolinepropanoic acid derivative
EINECS	Contact for details

Quality Control

Our Rebamipide is manufactured under strict quality management systems. Each batch is tested to ensure it meets high-purity standards suitable for pharmaceutical use, with comprehensive analytical profiles including HPLC, IR, and residual solvent analysis. A Certificate of Analysis (COA) is provided with every shipment to guarantee traceability and compliance.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept in a dry environment to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time conforms to reference standard
Assay (HPLC)	98.0% - 102.0% (on anhydrous basis)
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 0.5%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.