Description

3-[(1S)-1-(Dimethylaminoethyl)]Phenol is a chiral phenolic compound featuring a dimethylaminoethyl side chain, serving as a crucial advanced pharmaceutical intermediate. Its primary value lies in its role as a key building block for the synthesis of complex active pharmaceutical ingredients (APIs), particularly in chiral drug development. This high-purity intermediate is essential for manufacturers in the pharmaceutical and fine chemical sectors requiring precise stereochemistry and reliable quality for their synthesis processes.

Application

• Pharmaceutical Intermediate: A critical chiral building block for the synthesis of complex Active Pharmaceutical Ingredients (APIs), particularly in central nervous system (CNS) and cardiovascular drug categories.
• Asymmetric Synthesis: Utilized in the production of enantiomerically pure compounds where the (S)-configuration is required for biological activity.
• Ligand and Catalyst Precursor: Serves as a starting material for the development of chiral ligands and organocatalysts used in asymmetric catalysis.
• Fine Chemical Research: Employed in R&D laboratories for the discovery and development of new chemical entities with potential therapeutic value.
• Agrochemical Intermediate: Potential use in the synthesis of advanced, chiral agrochemicals requiring specific stereochemistry for efficacy.

Basic Information

Product Name	3-[(1S)-1-(Dimethylaminoethyl)]Phenol
CAS No.	139306-10-8
Molecular Formula	C10H15NO
Molecular Weight	165.23 g/mol
Synonyms	(S)-3-[1-(Dimethylamino)ethyl]phenol; (1S)-1-(3-Hydroxyphenyl)-N,N-dimethylethanamine; Phenol, 3-[(1S)-1-(dimethylamino)ethyl]-; 3-[(S)-1-(Dimethylamino)ethyl]phenol; (S)-1-(3-Hydroxyphenyl)-N,N-dimethylethylamine
EINECS	Contact for details

Quality Control

Our 3-[(1S)-1-(Dimethylaminoethyl)]Phenol is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity verification by HPLC, to ensure it meets the high standards required for pharmaceutical intermediate applications. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming identity, purity, and enantiomeric excess.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to prevent moisture absorption. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.