Description

Ethyl 8-Chloro-1-Ethyl-4-Oxo-4H-Quinolizine-3-Carboxylate is a high-purity, advanced pharmaceutical intermediate with a defined quinolizine core structure. This compound is critical for the synthesis of complex active pharmaceutical ingredients (APIs) and novel chemical entities in medicinal chemistry research. It is primarily utilized by R&D laboratories and production facilities in the pharmaceutical, agrochemical, and fine chemical industries seeking reliable, high-quality building blocks for complex synthesis.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel drug candidates, particularly those targeting neurological and anti-infective pathways.
• Agrochemical Research: Serves as a precursor for developing new herbicides and pesticides with specific modes of action.
• Organic Synthesis: Used in academic and industrial research for constructing complex heterocyclic compounds and exploring new chemical reactions.
• Material Science: Potential precursor for specialty chemicals and functional materials requiring specific photophysical properties.
• Contract Manufacturing (CMO): Supplied to contract manufacturing organizations for the production of client-specific target molecules under cGMP conditions.

Basic Information

Product Name	Ethyl 8-Chloro-1-Ethyl-4-Oxo-4H-Quinolizine-3-Carboxylate
CAS No.	139179-03-6
Molecular Formula	C14H16ClNO3
Molecular Weight	281.74 g/mol
Synonyms	8-Chloro-1-ethyl-4-oxo-4H-quinolizine-3-carboxylic acid ethyl ester; Ethyl 8-chloro-1-ethyl-4-oxoquinolizine-3-carboxylate; 1-Ethyl-8-chloro-4-oxo-1,4-dihydroquinolizine-3-carboxylic acid ethyl ester; Quinolizine-3-carboxylate derivative; 139179-03-6; 8-Chloro-1-ethyl-4-oxo-4H-quinolizine-3-carboxylate ethyl ester
EINECS	Contact for details

Quality Control

Our Ethyl 8-Chloro-1-Ethyl-4-Oxo-4H-Quinolizine-3-Carboxylate is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) is provided with each shipment, detailing all relevant specifications. We support development and commercial projects requiring compliance with ICH guidelines and cGMP standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and light-sensitive; therefore, containers must be kept tightly sealed and away from moisture and direct light exposure. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.