Description

Ethyl 8-Chloro-4-Oxo-4H-Quinolizine-3-Carboxylate is a high-value, synthetically versatile heterocyclic building block. This compound matters as a key intermediate in the synthesis of complex pharmaceutical molecules and advanced organic materials. It is primarily needed by research and development chemists, process development scientists, and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of novel quinolizine-based drug candidates, particularly for applications in medicinal chemistry research and development.
• Agrochemical Synthesis: Used in the development of new active ingredients for crop protection products, leveraging its heterocyclic core structure.
• Organic Light-Emitting Diodes (OLEDs): Serves as a building block for electron-transport or emissive layer materials in advanced display and lighting technologies.
• Ligand and Catalyst Development: Employed in the creation of specialized ligands for catalysis and metal-organic frameworks (MOFs).
• Academic and Industrial Research: A valuable reagent for method development and exploring new chemical spaces in heterocyclic chemistry.
• Dye and Pigment Intermediate: Used in the synthesis of specialized colorants and functional dyes due to its conjugated system.

Basic Information

Product Name	Ethyl 8-Chloro-4-Oxo-4H-Quinolizine-3-Carboxylate
CAS No.	139161-20-9
Molecular Formula	C12H10ClNO3
Molecular Weight	251.67 g/mol
Synonyms	Ethyl 8-chloro-4-oxo-4H-quinolizine-3-carboxylate; 8-Chloro-4-oxo-4H-quinolizine-3-carboxylic acid ethyl ester; 3-Quinolizinecarboxylic acid, 8-chloro-4-oxo-4H-, ethyl ester; Ethyl 8-chloro-4-oxoquinolizine-3-carboxylate; 139161-20-9
EINECS	Contact for details

Quality Control

Our Ethyl 8-Chloro-4-Oxo-4H-Quinolizine-3-Carboxylate is produced under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical specifications. Our quality commitment supports applications requiring high-purity intermediates for research and cGMP manufacturing.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (typically 15-25°C). This compound is light-sensitive (store away from light). Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 97.0%
Related Substances (HPLC)	Total impurities ≤ 3.0%
Any single impurity	≤ 1.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.