Description

(S)-Amino-(2-Fluoro-Phenyl)-Acetic Acid CAS NO 138751-04-9 is a high-purity, non-natural amino acid derivative featuring a chiral center and a fluorinated aromatic ring. This compound is a critical chiral building block for the synthesis of complex pharmaceutical intermediates and active ingredients. It is primarily utilized by research institutions and manufacturers in the pharmaceutical, agrochemical, and advanced material science sectors for developing novel therapeutics and specialty chemicals.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the research and production of APIs (Active Pharmaceutical Ingredients), particularly in oncology and CNS drug discovery.
• Peptide Synthesis: Used in solid-phase and solution-phase peptide chemistry to incorporate fluorinated phenylglycine analogs into peptide chains.
• Agrochemical Research: Serves as a precursor for developing novel herbicides and pesticides with enhanced biological activity and selectivity.
• Ligand and Catalyst Development: Employed in the design of chiral ligands for asymmetric catalysis and organometallic complexes.
• Diagnostic Reagent Manufacturing: Utilized in the synthesis of contrast agents or molecular probes for imaging applications.
• Academic & Industrial R&D: A valuable reagent for medicinal chemistry programs and structure-activity relationship (SAR) studies.

Basic Information

Product Name	(S)-Amino-(2-Fluoro-Phenyl)-Acetic Acid
CAS No.	138751-04-9
Molecular Formula	C8H8FNO2
Molecular Weight	169.15 g/mol
Synonyms	(S)-2-Amino-2-(2-fluorophenyl)acetic acid; (S)-2-Fluorophenylglycine; D-(−)-2-Fluorophenylglycine; (S)-α-Amino-2-fluorobenzeneacetic acid; L-2-Fluorophenylglycine (ambiguous); (2S)-2-Amino-2-(2-fluorophenyl)ethanoic acid; (S)-2-Fluoro-α-aminophenylacetic acid; FA 2-F-PG-OH
EINECS	Contact for details

Quality Control

Our (S)-Amino-(2-Fluoro-Phenyl)-Acetic Acid is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity verification by HPLC, to ensure it meets the high standards required for pharmaceutical R&D and production. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming identity, purity, and enantiomeric excess.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive); keep the container tightly sealed under an inert atmosphere for long-term storage to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Enantiomeric Excess (Chiral HPLC)	≥99.0%
Loss on Drying	≤0.5%
Residue on Ignition	≤0.1%
Heavy Metals	≤10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.