Description

Bupleuran 2Iic is a purified polysaccharide fraction derived from the roots of *Bupleurum falcatum* L. (Chinese Thoroughwax). This compound is valued for its specific biological activity and structural consistency, making it a critical reference standard and active ingredient in advanced research and development. It is primarily utilized by the pharmaceutical, nutraceutical, and academic research sectors for immunological studies, quality control of herbal extracts, and the development of novel therapeutic agents.

Application

• Pharmaceutical Reference Standard: Used for the identification, assay, and quality control of Bupleurum root extracts and related herbal preparations.
• Immunological Research: Serves as a key material for studying immunomodulatory activities, macrophage activation, and complement system pathways.
• Nutraceutical Development: Incorporated into high-grade dietary supplements targeting immune system support.
• Biochemical Research: Employed in structure-activity relationship (SAR) studies to understand the bioactive principles of traditional medicines.
• Herbal Medicine Standardization: Acts as a marker compound to ensure batch-to-batch consistency and potency in finished herbal products.
• Academic & Clinical Studies: Used in preclinical and clinical research to investigate the therapeutic potential of plant polysaccharides.

Basic Information

Product Name	Bupleuran 2Iic
CAS No.	138726-08-6
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	Bupleuran 2IIc; Bupleurum falcatum polysaccharide 2Iic; Bupleuri Radix polysaccharide fraction 2Iic; 2Iic-PS; BP2Iic; Arabinogalactan from Bupleurum falcatum (fraction 2Iic); (1→3)-, (1→6)-β-D-Galactan (from Bupleurum)
EINECS	Contact for details

Quality Control

Our Bupleuran 2Iic is produced under strict quality management protocols to ensure identity, purity, and biological consistency. Each batch is characterized using advanced analytical techniques including HPLC, HPSEC, and monosaccharide composition analysis. A comprehensive Certificate of Analysis (COA) detailing specifications such as carbohydrate content, protein residue, and spectral identification is provided to guarantee it meets the stringent requirements for research and development applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C. This material is hygroscopic (moisture-sensitive) and must be kept under desiccated conditions to maintain stability and prevent degradation. For long-term storage, consider keeping the container under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Identification (HPSEC)	Characteristic polysaccharide profile
Assay (Total Carbohydrate)	≥ 95.0% (by Phenol-Sulfuric Acid Method)
Protein Content	≤ 1.0% (by Bradford method)
Uronic Acid Content	≤ 5.0%
Loss on Drying	≤ 8.0%
Residue on Ignition	≤ 5.0%
Biological Activity	Complements classical pathway (Contact for details)

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.