Description

1,8-Diazabicyclo[5.4.0]undec-7-ene hydrotribromide is a high-purity, non-nucleophilic strong base reagent, specifically the hydrotribromide salt of the versatile DBU (1,8-Diazabicyclo[5.4.0]undec-7-ene). This compound matters for its ability to act as a powerful base and catalyst in sensitive organic synthesis where the free base form may be too volatile or reactive, offering improved handling and stability. It is primarily needed by R&D chemists and process engineers in the pharmaceutical, agrochemical, and advanced materials industries for demanding reactions such as dehydrohalogenation, esterification, and the synthesis of heterocycles.

Application

• Pharmaceutical Intermediate Synthesis: Acts as a crucial base and catalyst in the multi-step synthesis of active pharmaceutical ingredients (APIs), particularly for complex molecules.
• Polymerization Catalyst: Used as an efficient catalyst in the production of polyurethanes, polyamides, and other specialty polymers.
• Dehydrohalogenation Reactions: Facilitates the elimination of hydrogen halides from organic substrates to form alkenes or alkynes under controlled conditions.
• Esterification and Transesterification: Promotes the formation or exchange of ester groups in fine chemical and flavor/fragrance manufacturing.
• Heterocyclic Compound Formation: Essential for constructing nitrogen-containing ring systems like imidazoles, pyrimidines, and triazoles.
• Agrochemical Production: Employed in the synthesis of advanced herbicides, fungicides, and plant growth regulators.
• Research & Development: A valuable reagent in academic and industrial labs for methodological development and exploring new chemical spaces.
• Electronic Chemicals: Used in the synthesis of precursors for organic light-emitting diodes (OLEDs) and other electronic materials.

Basic Information

Product Name	1,8-Diazabicyclo[5.4.0]undec-7-ene Hydrotribromide
CAS No.	138666-59-8
Molecular Formula	C9H16N2·3HBr
Molecular Weight	428.87 g/mol
Synonyms	DBU Hydrotribromide; 1,8-Diazabicyclo[5.4.0]undec-7-ene Trihydrobromide; 2,3,4,6,7,8,9,10-Octahydropyrimido[1,2-a]azepine Trihydrobromide; DBU·3HBr; 1,8-Diazabicyclo[5.4.0]undec-7-ene Hydrobromide (3:1); DBU Tribromide Salt
EINECS	Contact for details

Quality Control

Our 1,8-Diazabicyclo[5.4.0]undec-7-ene hydrotribromide is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure high purity, consistency, and compliance with customer specifications. Comprehensive Certificates of Analysis (COA) detailing identity, assay, and impurity profiles are provided with every shipment. We support cGMP standards for pharmaceutical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and must be kept under dry, inert conditions to prevent degradation. Keep away from incompatible materials such as strong acids and strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.